background: the appropriate colon cleansing is a major determinant of quality of colonoscopy. the aim of this study was to compare the efficacy and tolerability of the morning (am) peg (polyethylene glycol) solution to previous-evening (pm) peg solution for the afternoon colonoscopy. methods: this comparative study compared the am to pm prep for afternoon outpatient colonoscopy. the subjects ra...

Primula auriculata (Tootia) is one of the most important local medicinal plants in Hamedan district, Iran. To investigate cytotoxicity and apoptosis induction of crude methanolic extract and different fraction of it we compared several methods on HT-29 human colon Adenocarcinoma cells. Cancer cell proliferation was measured by 3-(4, 5‑dimethylthiazolyl)-2, 5‑diphenyl‑tetrazolium bromide (MTT) a...

Objective(s): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions.  The present study was designed to determine whether dietary phytate affects mutation frequency in colon epithelial cells challenged with azoxymethane in vivo, through lowering the formation of O6-methyl guanosine (O6-MeG) and 8-hydroxy deoxyguanosine (8-OHdG) ad...

FIG. 1. Results of a barium enema showing a stricture of the descending colon. of Cobalt 60 was given in two parallel opposed fields (15 cm. x 15 cm.), which included the kidney bed and regional lymphatics. A dose of 300 r was given daily alternating between the anterior and posterior portal. A total dose of 5,500 r was delivered over 29 days. The patient remained at work until May 1963 (month ...

FIG. 1. Results of a barium enema showing a stricture of the descending colon. of Cobalt 60 was given in two parallel opposed fields (15 cm. x 15 cm.), which included the kidney bed and regional lymphatics. A dose of 300 r was given daily alternating between the anterior and posterior portal. A total dose of 5,500 r was delivered over 29 days. The patient remained at work until May 1963 (month ...

Background. 5-HT enhances dextran sulfate sodium- (DSS-) induced colitis and is involved in inflammatory bowel disease (IBD). Matrix metalloproteinases (MMPs) play roles in the process of intestinal inflammation. Aims. To examine whether 5-HT induces MMPs expression in mouse colon to enhance DSS-induced colitis. Materials and Methods. C57BL/6J (B6) mice were treated with either low-dose (1.0 mg...

Introduction Although faecal microbiota transplantation (FMT) appears to hold therapeutic potential for ulcerative colitis (UC), the optimal administration route and dose of FMT is unknown. This pilot trial aimed identify further test in an RCT. Methods In this prospective, three-centre, open-label, randomised study (STOP-Colitis pilot), we compared delivery via naso-gastric (...

This case report describes a patient with cutaneous signs in the genital and peri-anal region suspicious of Crohn’s disease without any intestinal symptom or sign. Inflammatory bowel disease can be associated with some cutaneous signs. However, in this paper, we report a patient with isolated cutaneous Crohn’s disease which is very rare (less than 100 case reports across the world). Our patient...