نتایج جستجو برای: complement 3

تعداد نتایج: 1868829  

Journal: :Neuroscience letters 2015
Elisa Merega Silvia Di Prisco Paolo Severi Fotios Kalfas Anna Pittaluga

Previous studies have demonstrated that complement alone releases glutamate from human and mouse cortical terminals in an antibody-independent manner. In order to expand our knowledge on complement-mediated effects, we investigated whether the presence of an antigen-antibody complex in synaptosomal plasmamembranes could also trigger complement-induced functional responses that might affect neur...

2013
Yansong Li Mikulas Chavko Jessica L Slack Bin Liu Richard M McCarron James D Ross Jurandir J Dalle Lucca

BACKGROUND Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury. We have recently demonstrated that blast-triggered complement activation and cytokine release are associated with BINT. Here, we evaluated if administration of ...

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