OBJECTIVES In failing mouse and human hearts, a shift in myosin heavy chain (MHC) isoform content from alpha to beta can occur. However, the impact of this phenomenon on disease progression is not well understood. Therefore, using transgenic (TG) mice, we tested how a pre-existing shift from alpha- to beta-MHC affects cardiac function under chronic mechanical or pharmacologic cardiovascular str...

Matrix-variate beta distributions are applied in different fields of hypothesis testing, multivariate correlation analysis, zero regression, canonical correlation analysis and etc. A methodology is proposed to generate matrix-variate beta generator distributions by combining the matrix-variate beta kernel with an unknown function of the trace operator. Several statistical characteristics, exten...

Let $p$ be an analytic function defined on the open unit disc $mathbb{D}$ with $p(0)=1.$ The conditions on $alpha$ and $beta$ are derived for $p(z)$ to be subordinate to $1+4z/3+2z^{2}/3=:varphi_{C}(z)$ when $(1-alpha)p(z)+alpha p^{2}(z)+beta zp'(z)/p(z)$ is subordinate to $e^{z}$. Similar problems were investigated for $p(z)$ to lie in a region bounded by lemniscate of Bernoulli $|w^{2}-1|=1$ ...