Examples Determine interaction between a known promoter and enhancer Determine comprehensively higher-order chromosome structure in a defi ned region All genes and genomic elements associated with a known LCR All intraand interchromosomal associations Determine the role of specifi c transcription factors in the interaction between a known promoter and enhancer Map chromatin interaction network ...

A novel class of light-responsive π-conjugated compounds incorporates photochromic torsional switches (PTS). These are able to tune the planarization their backbone, and thus optical electronic properties, by using light as an external stimulus. The PTS unit is based on a bithiophene fragment linked azobenzene moiety. When this PTS-containing oligothiophene not exposed light, moiety assumes its...

Exciting developments in the site-selective modification of peptide backbones are allowing an outstanding fine-tuning conformation, folding ability, and physico-chemical biological properties.