Correspondence to: Associate Professor Paul Monagle, Divisional of Laboratory Services, Royal Children’s Hospital, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia; paul.monagle@ wch.org.au _________________________ C ongenital heart disease, with a wide spectrum of severity, affects approximately 1% of all live births. The majority of congenital cardiac struct...

Congenital heart diseases are broadly defined as those cardiac anomalies that are present at birth. By their very nature, such defects have their origin in embryonic development. Congenital mitral valve regurgitation is a rare disease occurring in infancy or childhood. In up to 60% of cases, congenital anomalies of the mitral valve occur in association with other cardiac lesions, and often more...

CMR is valuable in the evaluation of congenital heart disease (CHD). Traditional flow imaging sequences involve cardiac and respiratory gating, increasing scan time and susceptibility to arrhythmias. We studied a real-time color-flow CMR system for the detection of flow abnormalities in 13 adults with CHD. All 16 congenital flow abnormalities previously detected by echocardiography were visuali...

Abstract Background and Aims Pulmonary arterial hypertension (PAH) is a common complication of congenital heart disease (CHD). There were several variables predictor mortality in PAH-CHD from previous studies, but study with shunts has never been done, especially Indonesia. This aims to identify independent predictors among adult shunt Dr. Sardjito Hospital, Yogyakarta, Method Results We conduc...

With the advances in congenital cardiac surgery and postoperative care, an increasing number of children with complex congenital heart disease now reach adulthood. There are already more adults than children living with a congenital heart defect, including patients with complex congenital heart defects. Among these adults with congenital heart disease, a significant number will develop ventricu...

The development of the membrane oxygenator for pediatric cardiopulmonary bypass has been an incorporation of ideology and technological advancements with contributions by many investigators throughout the past two centuries. With the pursuit of this technological achievement, the ability to care for mankind in the areas of cardiac surgery has been made possible. Heart disease can affect anyone ...

With improvements in surgical and medical management, patients with congenital heart disease (CHD) are often living well into adulthood. MRI provides critical data for diagnosis and monitoring of these patients, yielding information on cardiac anatomy, blood flow, and cardiac function. Though historically these exams have been complex and lengthy, four-dimensional (4D) flow is emerging as a sin...

Recent research has demonstrated that genetic alterations or variations contribute considerably to the development of congenital heart disease. Many kinds of genetic tests are commercially available, and more are currently under development. Congenital heart disease is frequently accompanied by genetic syndromes showing both cardiac and extra-cardiac anomalies. Congenital heart disease is the l...

Heart disease-related deaths are the highest in most societies and congenital heart diseases account for approximately 40% of prenatal deaths and over 20% of mortality in the first few months after birth. Congenital heart disease affects approximately 1% of all newborns and is the causative factor for more deaths within the first year of life as compared to all other genetic defects. Advances i...

Abstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas Congenital Cardiac Disease, which was first formal attempt to classify heart disease. The International Paediatric Code ( IPCCC ) is now utilized worldwide most recently become component Eleventh Revision Classification Diseases...