OBJECTIVE To assess the efficacy of arterial duct angioplasty in maintaining adequate ductal patency in neonates with critical pulmonary valve stenosis. PATIENTS Two neonates presenting with cyanosis due to critical pulmonary valve stenosis with severe right ventricular hypoplasia underwent percutaneous balloon dilatation of the pulmonary valve. Despite successful dilatation, both remained cy...

DURING the past decade definite progress has been made toward an understanding of the hemodynamic alterations and pathophysiologic aspects of Ebstein's anomaly of the tricuspid valve.1' 2 Moreover, an increased awareness of the characteristic clinical findings has resulted in an apparent increase in incidence of the disease. Largely as a result of careful pathologic studies, atypical forms of E...

Background 4D MR flow has shown to have advantages over standard cardiac magnetic resonance (CMR), offering both anatomical and functional information in just a single acquisition. Pulmonary stenosis and pulmonary regurgitation are common problems in follow-up of patients with congenital heart disease. In this study we tested flow quantification at the level of the pulmonary valve (forward and ...

BACKGROUND Recent advances in diagnosis and treatment have increased the life expectancy of patients with congenital heart disease. METHODS To investigate the prevalence of adult congenital heart disease (ACHD) in a large registry of patients over a 20-year period, we retrospectively assessed data of 14,012 males and 4,461 females who underwent clinically indicated cardiac catheterization fro...

THE anatomic sites at which obstruction to the egress of blood from the left ventricle may occur are three in number, as follows (fig. 1): the aorta, the aortic valve, and the subaortic region of the left ventricle. Obstruction in the aorta may involve one of two general areas, namely, (1) the arch or just beyond, the lesions taking the forms of classical coarctation, tubular hypoplasia, or int...

Children with congenital aortic stenosis have "excessive" left ventricular hypertrophy with reduced resting systolic wall stress that allows for supernormal ejection performance. If aortic stenosis is uncorrected, this pattern persists until adulthood. The effect of removing the aortic pressure gradient on left ventricular hypertrophy and wall stress in children with congenital aortic stenosis ...

DURING the past decade definite progress has been made toward an understanding of the hemodynamic alterations and pathophysiologic aspects of Ebstein's anomaly of the tricuspid valve.1' 2 Moreover, an increased awareness of the characteristic clinical findings has resulted in an apparent increase in incidence of the disease. Largely as a result of careful pathologic studies, atypical forms of E...

D URING THE 1980s the pediatric cardiac catheterization laboratory has undergone a transition from a diagnostic laboratory to a therapeutic suite where congenital cardiac abnormalities are not only evaluated but often can be treated. Therapeutic transcatheter procedures have been developed that can provide palliative or definitive therapy to children with a variety of congenital cardiovascular ...

UNLABELLED The extent of congenital heart disease in Cameroon remains largely unknown. The aim of this study was to determine the occurrence and pattern of congenital heart diseases in the Cardiac Centre of St Elizabeth Catholic General Hospital, situated in a rural area of Cameroon. METHODS Between November 2002 and November 2008, a population of 2 123 patients with suspected cardiac patholo...

The majority of congenital heart defects (CHDs) occur as isolated malformations, while approximately 25-30% of them are associated with extracardiac anomalies, in the setting of large or submicroscopic chromosomal anomalies, mendelian disorders, and malformation associations. Some types of CHD, such as atrioventricular canal defect and interrupted aortic arch, are more frequently found in assoc...