VACTERL association (OMIM 192350) is a non-random combination of multiple congenital malformations including vertebral, anal, cardiac, tracheoesophageal, renal and limb anomalies. The wide spectrum of defects suggests the occurrence of defective development during early embryogenesis. The authors report a case of a complex polymalformative association detected by ultrasound in the first trimest...

Repair of congenital groin hernia/hydrocele and orchidopexy for the undescended testis are the most common surgical procedure performed by pediatric surgeons. Up to 1% of all men have been reported to have a congenital unilateral absence of the vas deferens (CUAVD).1 Previous studies have suggested that ipsilateral renal anomalies are present in up to 91% of men with a congenital unilateral abs...

OBJECTIVE To determine the association between light-to-moderate prenatal alcohol exposure and congenital renal anomalies. METHODS Data from the population-based Atlanta Birth Defects Case-Control Study were used to examine the association between selected renal anomalies and self-reported maternal alcohol consumption during the period from 1 month before through 3 months after conception. Ca...

maternal hyperglycemia during early gestation is associated with an increased incidence of congenital anomalies. a case of mater­nal diabetes syndrome is presented here with a rare constellation of congenital anomalies, i.e., bifurcated distal pha­lanx of the thumb, patent ductus arteriosus and cleft lip.

developing supernumerary limbs is a rare congenital condition that only a few cases have been documented. depending on the cause and developmental conditions, they may be single, multiple or complicated, and occur as a syndrome or associated with other anomalies. polymelia is defined as the presence of extra limb(s) which have been reported in human, mouse, chicken, calf and lamb. it seems that...

Address for Correspondence: C.S. Ramesh Babu, Associate Professor of Anatomy, Muzaffarnagar Medical College, N.H.-58, Opp. Begrajpur Industrial Area, Muzaffarnagar-251203 (U.P), India. Mobile: +91-9897249202 E-Mail: [email protected] Background: Congenital positional, rotational and fusion anomalies of the kidney are frequently encountered. Crossed renal ectopia is a condition in which the ki...

Background and aims: Congenital anomalies are as the major causes of stillbirths, neonatal death, disability and childhood health problems all over the world. The aim of this study was to determine the incidence and pattern of congenital anomalies in newborn during the first 24 hours of life in Shahid-Madani hospital, Azarshahr, Tabriz, during two periods 2002-2003 and 2...

BACKGROUND Uroplakin (UP) proteins cover urothelial apical surfaces. Mice lacking UPIIIa have elevated urothelial permeability and congenital renal tract anomalies, and UPIIIa mutations have been reported in children with kidney and ureter malformations. Mice with null mutation of another UP family member, UPII, are often born with congenital hydronephrosis. We hypothesized that UPII mutations ...

introduction congenital microgastria is an extremely rare anomaly, which is due to failure of gastric development, and causes a tubular stomach with reduced capacity. it is almost always associated with other congenital anomalies. case presentation the patient was a two-month-old boy with microgastria in association with gastroesophageal reflux, tracheomalacia, and limb defect. discussion most ...