OBJECTIVE Drospirenone (DRSP) is a progestogen derived from spironolactone with antimineralocorticoid action that seems to exert a favorable effect on blood pressure (BP); however, when associated with ethinylestradiol (EE), this effect does not seem to occur. This study aimed to assess possible differences in BP associated with the use of combined oral contraceptives containing DRSP with diffe...

We carried out a retrospective cross-sectional study on 500 women in Isfahan who started taking combined oral contraceptives (COCs) during the period 21 March 1995-20 March 1997. The cumulative continuation rate fell from 77% to 12% over 60 months. The most common reason for discontinuation was side-effects. There was a significant correlation between side-effects and cumulative COC continuatio...

BACKGROUND There is a need to increase our knowledge regarding the influence of combined oral contraceptive (COC) use on individual weight change in the long term. The first aim of this study was to assess the long-term influence of COC's on body weight, and the second aim was to describe body weight increase during the fertile period. METHODS Postal questionnaires regarding weight/height, co...

Combined oral contraceptive pills (cOCPs) are often used in the treatment of acne in females. They are effective, safe, and easy to use in appropriate patients in combination with more conventional acne therapies. This article will briefly address the physiologic rationale for the use of cOCPs in the treatment of acne. It will also review efficacy by examining relevant clinical trials. Safety c...

Focusing on intrauterine contraceptives (IUC), contraceptive implants, and emergency contraceptives, we review recent advances in contraceptive development and discuss progress in policies to improve access to the most effective methods. We report on the shift in practice towards routinely providing IUCs and implants to young and nulliparous women, prompted in part by the reduced diameter of th...

I argue that opposition to contraception is not made any less implausible by the application of the Doctrine of Double Effect, as for example in the case of the recent argument according to which double effect can be deployed to make the prescription of Combined Oral Contraceptives compatible with Catholic teachings. I argue that opposition to contraception is not made any less implausible by t...

4.1 Absorption, distribution, metabolism and excretion The disposition of various formulations of oral contraceptives used in humans differs. In general, both the oestrogenic and progestogenic compounds in combined oral contraceptives are absorbed by the gut and metabolized largely in the liver. A fraction of the absorbed dose of ethinyloestradiol and several progestogens is excreted in the bil...

abstract it is becoming evident that oral hormonal contraceptives –besides being well established contraceptives – seem to become important medications for many functional or organic disturbances. so far, clinical effectiveness has been shown for treatment as well as prevention of menstrual bleeding disorders and menstrual-related pain symptoms. also this is true for premenstrual syndrome (pms)...

background: the reports of a rise in contraceptive practices have not been matched by a similar decrease in population: therefore, there is a need to look into the causes of this discrepancy. the objectives of this study were to determine the prevalence of different methods of contraception used by egyptian women, to compare different contraception methods used among various socio-demographic g...