Our aim was to clarify the correlation of attention deficit hyperactivity disorder (ADHD) with epilepsy and behavior problems. This was a cross-sectional study. Sixty children with idiopathic epilepsy were interviewed using the MTA-SNAP IV Teacher and Parent Rating Scale, Vineland Adaptive Behavior Scales and Conners' Rating Scales. We used the chi-square test to analyze the correlation of epil...

INTRODUCTION Attention Deficit Hyperactivity Disorder (ADHD) is a common comorbid condition in children with epilepsy and migraine. Treatment of ADHD in children with epilepsy or migraine is essential but clinicians may overlook symptoms of ADHD and avoid appropriate use of medications that may reduce symptoms of ADHD without compromising treatment of epilepsy or migraine. Areas covered: PubMed...

Generic (Brand) Name Clinical Uses Other Than Epilepsy Level of Evidence Acetazolamide (Diamox®) Bipolar disorder Open-label studies Tardive dyskinesia Positive placebo-controlled studies Carbamazepine (Equetro®, Tegretol®, and others) Aggression/agitation; benzodiazepine withdrawal; cocaine craving Positive placebo-controlled studies; open-label studies; negative placebo-controlled studies Alc...

Background: Epilepsy is a common non-communicable disease that affects both young and the elderly, with cumulative lifetime incidence of 3%. Bone health may be impacted by prolonged AED use, study aims to investigate relationships between long-term antiepileptic usage, vitamin D levels, other outcomes. Methods: Comparative observational research was conducted on 60 children 30 healthy controls ...

We report an unusual association between idiopathic occipital epilepsy and childhood absence epilepsy in 2 pediatric patients. At first clinical and electroencephalographic evaluation, the patients presented the peculiar signs of idiopathic occipital epilepsy Gastaut type: focal sensory visual seizures, migraine-like symptoms (only in one patient) and unilateral spike-wave discharges over occip...

We report on a 3-year-old boy with myoclonic-astatic epilepsy who developed myoclonic status epilepticus with continuous twitching of the face and unresponsiveness under monotherapy with levetiracetam. Recently, a nonconvulsive status epilepticus in an adult epilepsy patient has also been described. Our observation points to the possibility of a causal relationship between the induction of myoc...

Anti-glutamic acid decarboxylase (GAD) antibodies are described in stiff-person syndrome and also in other neurological syndromes, including cerebellar ataxia and epilepsy. This paper reports the case of a patient who had chronic focal epilepsy, upbeat nystagmus and cerebellar ataxia, associated with a polyautoimmune response including anti-GAD antibodies. Both gait and nystagmus improved marke...

Carbamazepine in the treatment of generalised tonic clonic seizures in juvenile myoclonic epilepsy Juvenile myoclonic epilepsy is characterised by bilateral myoclonic jerks on wakening, and generalised tonic clonic seizures with onset in the mid-teens, which may be preceded by typical absences in 33% of patients.' Findings on EEG include bilateral spikes or multiple spike-slow wave discharges a...

Mutations in the SCN1A gene can cause a variety of dominantly inherited epilepsy syndromes. Severe phenotypes usually result from loss of function mutations, whereas missense mutations cause a milder phenotype by altering the sodium channel activity. We report on a novel missense variant (p.Val1379Leu) in the SCN1A gene segregating in an autosomal dominant pattern in a family exhibiting a varia...

Many patients with mesial temporal lobe epilepsy continue to have seizures despite medical therapy. For these patients, one recourse is surgical resection of the mesial temporal lobe, with its attendant risks. Noninvasive treatment with Gamma Knife radiosurgery is under active investigation as a possible alternative to open surgery. Accumulated evidence from multiple studies shows radiosurgery ...