Gacyclidine, a novel, noncompetitive NMDA receptor antagonist, was injected (i.v.) into rats at three different doses to determine if the drug could promote behavioral recovery and reduce the behavioral and anatomical impairments that occur after bilateral contusions of the medial frontal cortex (MFC). In the Morris water maze, contused rats treated with gacyclidine at a dosage of 0.1 mg/kg per...

BACKGROUND For the past few years, treatment of contusions and associated symptoms, such as bruising, pain, and loss of function, has involved instrument-based therapies, ie, lasers, electromagnetic fields, and electrical stimulation. In this study, tissue optimization (TO) sessions were applied using a radioelectric asymmetric conveyor (REAC) for the treatment of contusions and associated symp...

Posttraumatic cerebral infarction is a rare complication and is an indicator of poor clinical outcome of head-trauma in spite of appropriate medical and surgical interventions. Cerebellar infarction following head trauma is also very rare and only a few reported cases are available in literatures. A 2-year-old child sustained head injury in a car accident and underwent surgery because of cerebr...

The authors present the frequency, clinical forms and therapeutic results of traumatic glaucoma in 511 injured eyes. Traumatic glaucoma was found in 6.6% of the injured eyes, more frequently in contusions than in perforating lesions of the eye. One third of the patients with traumatic glaucoma were blind and one half had visual acuity below 0.1. The time elapsed between the injury and the diagn...

Older infants suffer from tears at pontomedullary junction, petechial hemorrhages and cellular necrosis. By one year of age sutures are closed and skull becomes rigid. Glial cell proliferation, synaptic connections, and dendrites arborization progress logarithmically till two years of age. Myelinization begins at first year and progress till 10 year of life. Hence contusions, subarachnoid and e...

Speaking generally, the treatment of fractures in country districts is very unsatisfactory in South India. Out of 165 fractures of the metacarpals and phalanges seen from 1930-37, 85 per cent were treated as sprains and contusions in mofussil hospitals and by bone-setters. The result of such treatment was very marked I functional disability. Any injury which occurs ! at the metacarpophalangeal ...

Trauma is the leading cause of mortality in children over one year of age in industrialized countries. In this retrospective study we reviewed all chest trauma in pediatric patients admitted to Mansoura University Emergency Hospital from January 1997 to January 2007. Our hospital received 472 patients under the age of 18. Male patients were 374 with a mean age of 9.2±4.9 years. Causes were pene...

CONTEXT Mobile water within the bone marrow is a physiological phenomenon that is identifiable on magnetic resonance (MR) imaging, and signal changes can result from blood pooling, reactive hyperemia, edema, and microfracture. When these MR lesions are associated with an acute traumatic event, the findings are referred to as bone bruises and so represent a unique manifestation of injury. This r...

BACKGROUND Cerebral contusions have a 51% incidence of evolution in the first hours after injury. Evolution is associated with clinical deterioration and is the reason for ICP monitoring or surgical intervention. We sought to define CT features that predict cerebral contusion evolution. METHODS Patients treated for cerebral contusion who had 2 CT scans within 24 hours after injury were evalua...

Executive dysfunctions are among the most prevalent neurobehavioral sequelae of traumatic brain injuries (TBIs). Using culturally validated tests from the Delis-Kaplan Executive Function System (D-KEFS: Trail Making, Verbal Fluency, Design Fluency, Sorting, Twenty Questions, and Tower) and the Behavioural Assessment of the Dysexecutive Syndrome (BADS: Rule Shift Cards, Key Search, and Modified ...