CCORDING to previous analyses of 16 proline-requiring mutants of SalmonA d l a typhimurium, made genetically by NIELSEN (DEMEREC et al. 1954) and biochemically by JSANAZIR (1956; DEMEREC et al. 1955), the mutants fell into at least three groups. Recently, the number of proline-requiring mutants in our collection was increased to more than 200, and useful new techniques were devised or adapted f...

Prevalent folklore suggests that riots tend to occur during periods of very hot weather. Baron and Ransberger examined 102 major riots in the United States between 1967 and 1971 and concluded that the frequency of collective violence and ambient temperature are curvilinearly related. The present article points out that the Baron and Ransberger analysis did not take account of the different numb...

Crossover trials are widely used to assess the effect of a reversible exposure on an outcome of interest. To gain further insight into the underlying mechanisms of this effect, researchers may be interested in exploring whether or not it runs through a specific intermediate variable: the mediator. Mediation analysis in crossover designs has received scant attention so far and is mostly confined...

practice dating from medieval times) with increasingly concentrated and accurate firepower from rifled musketry and cannon. Thus Napoleon Bonaparte would lose over 40,000 dead and wounded in 2 days at the battle of Wagram (1809) while the murderous engagement at Antietam in the American civil war in September 1862 produced 1-day losses of 25,000 men, which rivaled even the fatalities of the Bri...

Researchers often conduct mediation analysis in order to indirectly assess the effect of a proposed cause on some outcome through a proposed mediator. The utility of mediation analysis stems from its ability to go beyond the merely descriptive to a more functional understanding of the relationships among variables. A necessary component of mediation is a statistically and practically significan...

We study the swimming of non-relativistic deformable bodies in (empty) static curved spaces. We focus on the case where the ambient geometry allows for rigid body motions. In this case, the swimming equations turn out to be geometric. For a small swimmer, the swimming distance in one stroke is determined by the Riemann curvature times certain moments of the swimmer. New Journal of Physics 8 (20...

The aim was to examine the use of computer and paper based systems in accident and emergency (A&E) departments in the management of patients who are frequent attenders. More than half of the A&E consultants in the Thames regions who were sent a questionnaire responded (44 of the 80). 82% of the respondents use such systems predominantly to monitor violent patients, those with Munchausen syndrom...

The effects of changes in nominal bargaining power, the proposal selection rule and discounting in legislative bargaining outcomes are investigated. The comparative static predictions of the Baron-Ferejohn (1989) model better organize behavior than does Gamson’s Law (1961). However, proposer power is not nearly as strong as predicted under Baron-Ferejohn as coalition partners refuse to take the...

Ultrasound-guided percutaneous biopsy of visceral organs in the abdomen has been in effect for many years. Paul Ehrlich is credited with performing the first percutaneous liver biopsy in 1883 in Germany. Schüpfer in 1907 published the first liver biopsy series. Huard and Baron popularized liver biopsy for general purposes in the1930s. Some of the more contemporary articles reporting ultrasound-...