AIM to identify the difference between coronary angiography in patients with acute coronary syndrome (ACS) aged 45 years and those aged >45 years. METHODS a total of 322 ACS patients who underwent coronary angiography in ICCU of Cipto Mangunkusumo Hospital, Jakarta between January 2008 and December 2012 were included in this study. The severity of coronary stenosis was determined by vessel sc...

Recent studies from this laboratory have indicated that sympathetic a-receptor-mediated coronary vasoconstriction can compete with local metabolic vasodilation to reduce the oxygen supply to the myocardium. In vitro studies from other laboratories on isolated coronary vessel strips suggest that large epicardial vessels are the dominant site of adrenergic a-receptor activity. In this study we us...

The optimal revascularization strategy for patients with multi-vessel coronary artery disease remains controversial. The advent of percutaneous coronary intervention (PCI) has challenged the superiority of coronary artery bypass graft (CABG) surgery for multi-vessel disease. In the late 1990s, an integrated approach, now referred to as “hybrid coronary revascularization” (HCR), was pioneered co...

Recent studies from this laboratory have indicated that sympathetic alpha-receptor-mediated coronary vasoconstriction can compete with local metabolic vasodilation to reduce the oxygen supply to the myocardium. In vitro studies from other laboratories on isolated coronary vessel strips suggest that large epicardial vessels are the dominant site of adrenergic alpha-receptor activity. In this stu...

Aims: The purpose of this project was to determine the percentage of the lumen area to the whole vessel area of normal coronary and stenotic coronary in humans at postmortem, to compare the difference between the value of measurement to coronary samples and slices, and finally to provide a reference for assessing the coronary stenosis severity. Methods and Results: Image Analyze software was us...

The goal of this study was to determine the severity of vessel foreshortening in standard angiographic views used during percutaneous coronary intervention (PCI). Coronary angiography is limited by its two-dimensional (2D) representation of three-dimensional (3D) structures. Vessel foreshortening in angiographic images may cause errors in the assessment of lesions or the selection and placement...

Due to their relatively small size and central location within the thorax, improvement in signal-to-noise (SNR) is of paramount importance for in vivo coronary vessel wall imaging. Thus, with higher field strengths, coronary vessel wall imaging is likely to benefit from the expected "near linear" proportional gain in SNR. In this study, we demonstrate the feasibility of in vivo human high field...

Objective Biochemical indicators such as N-terminal pro-brain type natriuretic peptide (NT pro-BNP) and high-sensitivity Creactive protein (hsCRP) predict mortality in acute coronary syndrome (ACS). However, little is known about the relationship of these factors with severity of coronary artery stenosis in patients with. Methods Three hundred and thirty-one subjects including 246 unstable angi...

Since its introduction, percutaneous coronary intervention (PCI) has been limited by 2 major factors: restenosis and vessel closure attributable to thrombosis. The use of coronary stents has had a marked beneficial impact on rates of restenosis.1,2 However, the vessel trauma that occurs during PCI induces platelet activation, and all currently available coronary stents are made of metal and are...

Introduction: Coronary artery anomalies are rare clinical entities reported in 0.6% to 5.6% of diagnostic coronary angiographies. Anomalous origins of coronary arteries from distal segments are rarely reported. Presented herein is a coronary anomaly in which the circumflex artery (CX) originated as a continuation of the posterolateral branch of the right coronary artery (RCA) w...