Introduction Organic tissues are composed of the cells and the extracellular milieu. The external environmental stimuli may induce several cellular activities inside the tissue which in turn can vary tissue matrix. Such stimuli can be mechanical, hormonal, chemical or electrical etc. In the case of mechanical stimuli, the cells within the subjected tissue undergo a few aspects of the mechanical...

In the last years there has been a great interest in cortical bone investigation. In fact cortical bone porosity is considered one of the main parameters which determines bone strength [3, 8]. Even if histology has been the gold standard for the morphometric examination of bone specimens, in the last ten years a new method arose: X-ray microtomography (micro-CT). It permits the non-destructive ...

BACKGROUND Bovine pericardium collagen membrane (BPCM) had been widely used in guided bone regeneration (GBR) whose manufacturing process usually required chemical cross-linking to prolong its biodegradation. However, cross-linking of collagen fibrils was associated with poorer tissue integration and delayed vascular invasion. OBJECTIVE This study evaluated the potential of bovine cortical bo...

The elastic moduli of human subchondral, trabecular, and cortical bone tissue from a proximal tibia were experimentally determined using three-point bending tests on a microstructural level. The mean modulus of subchondral specimens was 1.15 GPa, and those of trabecular and cortical specimens was 4.59 GPa and 5.44 GPa respectively. Significant differences were found in the modulus values betwee...

OBJECTIVES This study evaluated the effect of magnesium dietary deficiency on bone metabolism and bone tissue around implants with established osseointegration. MATERIALS AND METHODS For this, 30 rats received an implant in the right tibial metaphysis. After 60 days for healing of the implants, the animals were divided into groups according to the diet received. Control group (CTL) received a...

Bone tissue and geometry are constantly modified through modeling and remodeling at the periosteal, endosteal and intracortical envelopes. Results from several studies indicate that femoral bone geometry is a predictor of whole bone strength (e.g. femoral neck strength), however, it is not known whether there is a relationship between bone structural and material properties. Bone geometry can b...

Exposed bone Exposed or denuded bone is a common complication of wounds of the distal aspect of the limb. Exposed cortical bone in which the periosteum has been removed, is prone to desiccation of the superficial layers of the cortex, which may result in infectious superficial osteitis and sequestrum formation. Exposed bone within a wound can delay wound healing directly if the bone becomes inf...

High treatment failure rates and the need for prolonged antimicrobial therapy for osteomyelitis and implant-associated infections suggest that antimicrobial bone penetration may be incomplete. Assessment of the bone pharmacokinetics of antimicrobials is challenged by a lack of validated methods. In this study, 1000 mg of vancomycin was administered as a single dose over 100 min to eight female ...

Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical properties. Estimates from whole bone testing suggest that material properties are negatively affected, though tissue-level assessmentshavenot been conducted. Therefore, the goal of the present study ...

INTRODUCTION To obtain sufficient stability of implants, the thickness of the soft tissue and the cortical bone in the placement site must be considered. However, the literature contains few anatomical studies of orthodontic implants. METHODS To measure soft-tissue and cortical-bone thicknesses, maxillae from 23 Korean cadavers were decalcified, and buccopalatal cross-sectional specimens were...