JOSEPH F. Ross, M.D., Editor

background: the aim of this study is to evaluate the association between different treatments and survival time of breast cancer patients using either standard cox model or stratified cox model. methods: the study was conducted on 15830 women diagnosed with breast cancer in british columbia, canada.  they were divided into eight groups according to patients’ ages and stage of disease either cox...

We describe a full maximum-likelihood fitting method of the popular single-factor Vasicek and Cox–Ingersoll–Ross models and carry this out for term-structure data from the UK and US. This method contrasts with the usual practice of performing a day-by-day fit. We also compare the results with some more crude econometric analyses on the same data sets. © 2000 Elsevier Science B.V. All rights res...

JOSEPH F. Ross, M.D., Editor

background: the omega-3 (ω-3) fatty acid eicosapentaenoic acid (epa) is currently used in the clinic as a nutritional supplement to improve infertility, particularly in women with polycystic ovarian syndrome (pcos).objective: the present study was designed to investigate the effect of epa on insulin-like growth factor 1 (igf-1) and cyclooxygenase 2 (cox-2) gene expression in primary cultured gr...