Background Previous studies have indicated that ingestion of nitric oxide (NO) supplements prior to exercise may potentially enhance anaerobic performance. Collectively, NO products are marketed to increase energy, strength, stamina and endurance during anaerobic exercise. However, delivery modes and formula combinations of NO supplements differ in regards to other nutrients included (i.e., cre...

During the past decade, the nutritional supplement creatine monohydrate has been gaining popularity exponentially. Introduced to the general public in the early 1990s, shortly after the Barcelona Olympic Games, creatine (Cr) has become one of the most widely used nutritional supplements or ergogenic aids, with loading doses as high as 20-30 g·day(-1) for 5-7 days typical among athletes. This pa...

The purpose of this study was to compare changes in muscle insulin-like growth factor-I (IGF-I) content resulting from resistance-exercise training (RET) and creatine supplementation (CR). Male (n=24) and female (n=18) participants with minimal resistance-exercise-training experience (=1 year) who were participating in at least 30 min of structured physical activity (i.e., walking, jogging, cyc...

BACKGROUND The objective was to study nutritional supplement use among young elite UK athletes to establish whether a rationale versus practice incongruence exists, and to investigate the sources of information. Survey data were analysed for association between supplements used and motives for using such substances among young athletes along with the sources of advice and literature precedents ...

Creatine (Cr) is an important high-energy phosphate buffer in tissues with a high energy demand such as muscle and brain and is consequently a highly consumed nutritional supplement. Creatine is synthesized via the S-adenosylmethionine (SAM) dependent methylation of guanidinoacetate (GAA) which is not regulated by a feedback mechanism. The first objective of this study was to determine the effe...

Creatine exerts beneficial effects on a variety of pathologies in which energy metabolism and oxidative stress play an etiological role. Creatine supplements have shown beneficial effects on neurological disorders including Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, Alzheimer's disease and stroke. However, the potential benefits of creatine for patients with convu...

The aim of this study is to compare the acute effects different creatine loading methods on anaerobic performance in soccer players. Totally 21 healthy male players participated study. was conducted a randomized and double-blind design. Athletes were loaded with 3 days. supplementation as follows; athletes took supplement 4 times day for 15 days, 4x5 grams first 5 days g following 10 In other c...

Creatine is recognized as a dietary staple among athletes, with two supplement formulations currently available on the United States market: creatine monohydrate and hydrochloride. has relatively low aqueous solubility, which hampers its ease of preparation by consumers. hydrochloride excellent solubility; however, it exhibits strong acidic taste potentially harmful effects dental health. Herei...

1. A randomized, double-blind, placebo-controlled trial utilizing creatine as a potential lipid-lowering agent was conducted to determine plasma lipid, lipoprotein, glucose, urea nitrogen and creatinine profiles in men and women ranging in age from 32 to 70 years. 2. Thirty-four subjects (18 men and 16 women) with total cholesterol concentrations exceeding 200 mg/dl received either a creatine s...