نتایج جستجو برای: cystein
تعداد نتایج: 282 فیلتر نتایج به سال:
We construct a graphical representation of protein structure based on the 3D C-alpha carbon point set, using the Delaunay tessellation to define interacting quadruples of amino acid residues. The tessellation is filtered by two criteria: interaction distance less than 9.5 angstroms and circumsphere radius less than 8.0 angstroms using dataset of 608 protein structures of low mutual sequence ide...
Chagas disease is one of the most important parasitic diseases in Latin America, affecting 16 to 18 million people. Nifurtimox and Benznidazol are drugs that are commonly used in its treatment; however, these drugs produce several adverse reactions and are not effective in the chronic phase of the disease. Therefore, the design, synthesis, and biological evaluation of new compounds with potenti...
Diazotized 3-aminopyridine adenine dinucleotide has been found to modify four sulfhydryl groups per molecule of enzyme during the complete inactivation of yeast alcohol dehydrogenase. The reaction of sulfhydryl groups was indicated by titration studies with 5,5-dithiobis(2-nitrobenzoic acid) as well as isolation and quantitation of the cysteinyl derivative released by acid hydrolysis of the mod...
Sweet potato belongs to Ipomoea series batatas and is thought to have originated in Central America and Northern South America. World sweet potato production is around 106 million tons in an area of about 8.1 million ha. Asia is the world’s largest sweet potato-producing region and China is the world’s leading sweet potato-producing country accounting for about 76% of production. Sweet potato h...
We report here the complete variable (V) region sequence of a nonfunctionally rearranged Vk gene from the BAIB/c derived myeloma cell line P3X63-Ag 8.653, which is the most ouinon fusion partner used in hybridoma technology. Corresponding cDtft clones were isolated from 2 independent cDNA libraries to autoantibody-secreting hybridoma lines in which they occured at a frequency of about 5% of fun...
Improved oxidative status in major abdominal surgery patients after N-acetyl cystein supplementation
BACKGROUND Increased levels of reactive oxygen species during and after surgery may affect inflammatory response, post-operative adhesion molecule formation, and hemodynamic stability. The glutathione redox cycle is an important regulator in oxidative stress and its reduced forms scavenge free radicals. N-acetyl cysteine, a precursor of reduced glutathione, is considered as a potentially therap...
Introduction: 3-4, methylenedioxymethamphetamine (MDMA) causes apoptosis in nervous system and several studies suggest that oxidative stress contributes to MDMA-induced neurotoxicity. The aim of this study is to examine the effects of N-acetyl-L-Cystein (NAC) as an antioxidant on MDMA-induced apoptosis. Methods: 21 Sprague dawley male rats (200-250mg) were treated with MDMA (2×0,5mg/kg) or MDMA...
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