To better understand the mechanism underlying the hepatocellular carcinoma (HCC) metastasis and to search potential markers for HCC prognosis, differential proteomic analysis on two well-established HCC cell strains with high and low metastatic potentials, MHCC97-H and MHCC97-L, was conducted using two-dimensional gel electrophoresis followed by matrix-assisted laser desorption/time-of-flight m...

Introduction. Currently, there are limited papers on changes in the pseudostratified ciliated columnar epithelium of sinonasal tract chronic inflammatory processes, particularly basal cell hyperplasia. The latter is similar to dysplasia varying severity stratified squamous nonkeratinized epithelium. Studying can clarify histogenesis various epithelial tumors tract, including papillomas. researc...

background and objective: nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. cytokeratins (ck) are intermediate filament proteins that provide mechanical support in epithelial cells. the purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. mate...

We present the case of a 72-year-old woman with invasive lobular breast carcinoma, stage IV (vertebral metastasis), and with recent-onset constipation. Digital rectal examination revealed increased consistency of the rectal wall. Laboratory test showed only elevation of CEA-II (28'3). Rectoscopy showed a partial stenosis of the rectal lumen, extending from the internal anal margin to about 10 c...

Our study examined whether human bone marrow-derived MSCs are able to differentiate, in vitro, into functional epithelial-like cells. MSCs were isolated from the sternum of 8 patients with different hematological disorders. The surface phenotype of these cells was characterized.To induce epithelial differentiation, MSCs were cultured using Epidermal Growth Factor, Keratinocyte Growth Factor, He...

Diffuse sclerosing variant (DSV) is a rare variant of papillary thyroid carcinoma (PTC) and its features have not yet been fully characterized. The aim of this case report is to analyze the immunohistochemistry profile of this disease and to highlight this rare entity. We analyzed the histology and immunohistochemistry of a female patient admitted in the Surgery Department of the "Sf. Ioan" Eme...

A 7-year-old Duroc sow exhibited emaciation, loss of appetite and rapid breathing, and was euthanized. Histopathological examination revealed mild to moderate fibrosis of the heart, cystic kidneys and ulcerative enteritis associated with Balantidium infection. Additionally, a small nodule was incidentally found in the peripancreatic fat tissue. The nodule consisted of disarranged cellular compo...

This report describes a case of multicentric intrahepatic biliary cystadenoma observed in a 13-year-old, male, Irish setter dog. The dog had a history of chronic inappetence, weight loss, intermittent icterus, and diarrhoea. In the ultrasonographic examination of the abdominal organs, 5 spherical masses were found in various liver lobes. The largest mass was 12 cm in diameter and was located on...