The main function of the skin is to protect the body against exogenous substances. The skin barrier is located in the outermost layer of the skin, the stratum corneum. This layer consists of keratin enriched cells embedded in lipid lamellae. These lamellae form the main barrier for diffusion of substances through the skin. In diseased skin the barrier function is often impaired. For a full unde...

Workers, both in the military and the commercial airline industry, are exposed to jet fuel by inhalation and dermal contact. We present a dermatotoxicokinetic (DTK) model that quantifies the absorption, distribution, and elimination of aromatic and aliphatic components of jet fuel following dermal exposures in humans. Kinetic data were obtained from 10 healthy volunteers following a single dose...

I . INTRODUCTION Estimators of the variance of estimators of total or mean using auxil iary information under a one primary sampling unit (PSU) per stratum sample design have been proposed by several authors. Under a one PSU per stratum sample design, the most common variance estimator of the usual estimator of total is the collapsed stratum variance estimator (Cochran (1977)) which has positiv...

Skin constitutes an excellent barrier for the transdermal delivery of hydrophilic or high molecular weight drugs. Low efficacy demonstrated in clinical trials for some topical drugs is mainly due to low skin penetration ability related to the efficient barrier properties of stratum corneum (SC). Transdermal delivery of molecules in the skin is limited by the full epidermis, not just stratum cor...

Skin constitutes an excellent barrier for the transdermal delivery of hydrophilic or high molecular weight drugs. Low efficacy demonstrated in clinical trials for some topical drugs is mainly due to low skin penetration ability related to the efficient barrier properties of stratum corneum (SC). Transdermal delivery of molecules in the skin is limited by the full epidermis, not just stratum cor...

The projections from the cerebellar nuclei to the superior colliculus of the cat have been studied by injecting small amounts of horseradish peroxidase into the colliculus and charting the distribution of the labeled neurons in the cerebellar nuclei. The results show that the cerebellar nuclei project to the deep layers of the superior colliculus, especially contralaterally. Of the deep cerebel...

The natural function of the skin is to protect the body from unwanted influences from the environment. The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Since the lipids regions in the stratum corneum form the only continuous structure, substances applied onto the skin always have to pass these regions. For this reason the organization in the lipid...

This paper’s centre of attention is on the problem of data mining (in general) and clustering (in specific) on a hidden web data. We know that data mining is a process that analyzes and extracts knowledge from large amounts of data which provides useful information to users. Hidden or deep web data is the database located at remote system .So, to access such data, we need query interface or HTM...

Using an antibody against tyrosine hydroxylase on newborn to 30-day kitten retinas, we have been able to follow the development of the dopaminergic amacrine cells of the cat retina by light-microscopical investigations of retinal wholemounts. The Type 1 or large Toh+ amacrine cells described by others (Oyster et al., 1985; Törk & Stone, 1979) and named A18 from a Golgi study (Kolb et al., 1981)...