In this paper, we present a new approach to tackle simultaneously linear and deformable registration between two images. Our combined formulation avoids the bias created when linear registration is performed independently before a deformable registration. Our registration problem is formulated as a discrete Markov Random Field and a higher order objective function. Usually, a grid is superimpos...

Deformable (non-rigid) registration is an essential tool in both adaptive radiation therapy and image-guided radiation therapy to account for soft-tissue changes during the course of treatment. The evaluation method most commonly used to assess the accuracy of deformable image registration is qualitative human evaluation. Here,we propose a method for systematically measuring the accuracy of an ...

The quality of adaptive treatment planning depends on the accuracy of its underlying deformable image registration (DIR). The purpose of this study is to evaluate the performance of two DIR algorithms, B-spline-based deformable multipass (DMP) and deformable demons (Demons), implemented in a commercial software package. Evaluations were conducted using both computational and physical deformable...

PURPOSE Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) shows high sensitivity in detecting breast cancer. However, its performance could be affected by patient motion during the imaging. To overcome this problem, it is necessary to correct patient motion by deformable registration, before using the DCE-MRI to detect breast cancer. However, deformable registration of DCE-MR image...

Multi-fraction cervical cancer brachytherapy is a form of image-guided radiotherapy that heavily relies on 3D imaging during treatment planning, delivery, and quality control. In this context, deformable image registration can increase the accuracy of dosimetric evaluations, provided that one can account for the uncertainties associated with the registration process. To enable such capability, ...

Non-rigid image registration is an interesting and challenging research work in medical image processing, computer vision and remote sensing fields. In order to increase the registration accuracy, this paper designs a composite registration algorithm of a rigid transform and free form deformation. Because NURBS (Non-uniform Rational B Spline) with a non-uniform grid has a higher registration pr...

We introduce a novel discrete optimization method for non-rigid image registration based on the random walker algorithm. We discretize the space of deformations and formulate registration using a Gaussian MRF where continuous labels correspond to the probability of a point having a certain discrete deformation. The interaction (regularization) term of the corresponding MRF energy is convex and ...

The paper describes a novel multi-resolution registration method. It is fast, robust and offers high registration accuracy. The algorithm models deformations using an elastic spring mass system, which contains sparse masses interconnected by springs. The proposed method uses data intensity values to guide deformation with local constraints imposed by interaction of interconnecting springs. More...

PURPOSE To validate and compare the deformable image registration and parotid contour propagation process for head and neck magnetic resonance imaging in patients treated with radiotherapy using 3 different approaches-the commercial MIM, the open-source Elastix software, and an optimized version of it. MATERIALS AND METHODS Twelve patients with head and neck cancer previously treated with rad...