elanocytes causing depigmentation at the periphery of melanocytic nevi. Clinically and dermoscopically these lesions can be difficult to distinguish from melanoma. Our case report shows our approach safe non-invasive monitoring using reflectance confocal microscopy 3-GEP PLA tests.

Occupational Leukoderma in Workers Engaged in 4-(p-Hydroxyphenyl)-2-Butanone Manufacturing: Yoshiharu FUKUDA, et al. Department of Public Health, Kumamoto University School of Medicine—Occupational leukoderma was found to be caused by exposure to depigmentation agents. This is the first report associated with the depigmenting activity of 4-(p-hydroxyphenyl)-2-butanone and its crude products. Th...

Depigmentation and skin lightening products, which have been in use for ages in Asian countries where skin whiteness is a major esthetic criterion, are now also highly valued by Western populations, who expose themselves excessively to the sun and develop skin spots as a consequence. After discussing the various possible mechanisms of depigmentation, the different molecules that can be used as ...

Patients with Tietz syndrome have congenital profound deafness and generalised hypopigmentation, inherited in a fully penetrant autosomal dominant fashion. The pigmentary features and complete penetrance make this syndrome distinct among syndromes with pigmentary anomalies and deafness, which characteristically have patchy depigmentation and variable penetrance. Only one family has been reporte...

Excessive gingival display space and gingival hyperpigmentation are major concerns for a large number of patients visiting the dentist. Melanin hyperpigmentation usually does not present a medical problem, but patients usually complain of dark gums as unaesthetic. This problem is aggravated in patients with a "gummy smile" or excessive gingival display while smiling. Esthetic periodontal plasti...

Vitiligo is a common skin disorder that results in depigmentation. With the appropriate management, many patients can minimize disease progression, attain repigmentation, and achieve cosmetically pleasing results. There are numerous medical and surgical treatments aimed at repigmentation; therapies for depigmentation are available for patients with recalcitrant or advanced disease. The use of c...

Vitiligo is an acquired hypomelanotic disorder characterized by the absence of melanocytes. The mechanism melanocyte loss remains unclear. In this study, we aimed to explore underlying mechanism. By electron microscopy and immunohistochemistry, branching fragmented basement membranes (BM) were identified in vitiligo skin. To determine why BM was altered vitiligo, expression matrix metalloprotei...

Shrimp shell waste contains chitin compounds which are useful in the food sector. The synthesis of into chitosan can be as an edible coating on tomatoes. research was conducted three stages: manufacturing process, antibacterial test chitosan, and application manufacture consisted isolation (deproteination, demineralization, depigmentation, deacetylation) characterization (moisture content, ash ...