The occurrence of opportunistic infections is not rare during the treatment of connective tissue diseases, including dermatomyositis because of the patient's immunosuppression. We describe here cytomegalovirus (CMV) infection that affected two of our patients with dermatomyositis. CMV infection has not been considered to be a frequent event in dermatomyositis, and its significance for disease p...

References 1. McCann LJ, Juggins AD, Maillard SM, Wedderburn LR, Davidson JE, Murray KJ, Pilkington CA: Juvenile Dermatomyositis Research Group. The Juvenile Dermatomyositis National Registry and Repository (UK and Ireland)–clinical characteristics of children recruited within the first 5 yr. Rheumatology 2006, 45(10):1255-1260. 2. Laskin BL, Choyke P, Keenan GF, Miller FW, Rider LG: Novel gast...

Dermatomyositis, a connective tissue disorder, is an idiopathic inflammatory myopathy characterised by skin manifestation. The diagnosis of dermatomyositis based on rashes the skin, progressive muscle weakness, elevated serum enzymes, abnormal electromyogram, and findings biopsy. Hereby presenting this rare case 57-year-old female with all typical clinical interstitial lung disease.

INTRODUCTION The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic muscle inflammation resulting progressive weakness and frequent involvement of internal organs, mainly the pulmonary, gastrointestinal and cardiac systems. OBJECTIVE To present clinical characteristics, disease course, frequency of relapses and survival of 79 patients with juvenile or...

UNLABELLED Dermatomyositis is an inflammatory myopathy with skin manifestations. In the adult over the age of 50 years, it can be associated with malignant neoplasias, being, thus, a signal of malignancy. OBJECTIVE To show the association of dermatomyositis of atypical presentation with two synchronous tumors, usually not related to that. CASE REPORT We report the case of a 72-year-old male...

Aims: To assess the contribution of electron microscopy in the process of muscle biopsies evaluation for dermatomyositis. Study Design: Retrospective review of muscle biopsy cases. Place and Duration of Study: Pathology Department of King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia from January 2008 to January 2012. Methodology: Samples from cases suspected to have de...

BACKGROUND Hemophagocytic lymphohistiocytosis associated with autoimmune diseases is seen in patients with systemic juvenile idiopathic arthritis, adult-onset Still's disease, and systemic lupus erythematosus, whereas it is rarely seen in patients with dermatomyositis. In addition, central nervous system involvement with dermatomyositis is rare. To the best of our knowledge, this is the first c...

INTRODUCTION Dermatomyositis is a condition well-known to medical physicians, especially rheumatologists and dermatologists. Classically, patients present with typical cutaneous features and proximal muscle weakness. Amyopathic dermatomyositis has been reported in recent literature where patients present with skin changes without muscle involvement. MATERIALS AND METHODS We reviewed 28 patien...

OBJECTIVES Systemic sclerosis (scleroderma) and dermatomyositis are two prototypic autoimmune diseases that are strongly associated with malignancy. While specific autoantibodies in these diseases are markers of an increased risk of cancer at scleroderma and dermatomyositis onset, it is not known whether these autoantibodies are biomarkers of cancer risk in patients without rheumatic disease. ...

Dermatomyositis is an uncommon inflammatory myopathy associated with cutaneous manifestations. It may also occur as paraneoplastic syndrome associated with various malignancies, most common of which being lung, breast, stomach, rectum, kidney, or testicular cancer. A postmenopausal woman presented to us with generalized itching along with skin rash and proximal muscle weakness of 2 years' durat...