Background: In specific immunotherapy (SIT), modified extracts have been used to allow safe administration of higher allergen doses. Schedules reaching maintenance doses in approximately 1 month, which may have greater efficacy, have even been proposed. Aims: To assess the safety and efficacy of SIT with modified (depigmented and polymerized) Dermatophagoides pteronyssinus extract in the treatm...

BACKGROUND Although sublingual immunotherapy (SLIT) has been demonstrated to be a safe and efficient treatment in children with seasonal allergic rhinitis (AR), there is little evidence on the efficacy of SLIT with house-dust-mite (HDM) extract in children with isolated perennial AR. OBJECTIVES We sought to assess the clinical efficacy and safety of HDM-SLIT in children with isolated allergic...

Summary House dust mites are among the most important allergy triggers worldwide. While of genus Dermatophagoides occur almost worldwide, tropical mite Blomia tropicalis and storage only importance for certain areas or groups people. The allergens pteronyssinus Der p 1, 2, 23 with immunoglobulin E (IgE)-binding frequencies more than 70% high allergenic activity. Also 5, 7, 21, which have IgE-bi...

371 Cutaneous Response to Patch Tests with Dermatophagoides Farinae and Dermatophagoides Pteronyssinus in Patients with Chronic Rhinitis Diego Garcia-Calderin, MD, Sandra González-Díaz, MD, PhD, Alfredo Arias-Cruz, MD, Alejandro Rojas, MD, Marisela Hernandez, MD, Claudia Gallego, MD, Karla Mejia, MD, Maricruz Calva, MD, and Luis Dominguez, MD. Regional Centre of Allergy and Clinical Immunology,...

371 Cutaneous Response to Patch Tests with Dermatophagoides Farinae and Dermatophagoides Pteronyssinus in Patients with Chronic Rhinitis Diego Garcia-Calderin, MD, Sandra González-Díaz, MD, PhD, Alfredo Arias-Cruz, MD, Alejandro Rojas, MD, Marisela Hernandez, MD, Claudia Gallego, MD, Karla Mejia, MD, Maricruz Calva, MD, and Luis Dominguez, MD. Regional Centre of Allergy and Clinical Immunology,...

371 Cutaneous Response to Patch Tests with Dermatophagoides Farinae and Dermatophagoides Pteronyssinus in Patients with Chronic Rhinitis Diego Garcia-Calderin, MD, Sandra González-Díaz, MD, PhD, Alfredo Arias-Cruz, MD, Alejandro Rojas, MD, Marisela Hernandez, MD, Claudia Gallego, MD, Karla Mejia, MD, Maricruz Calva, MD, and Luis Dominguez, MD. Regional Centre of Allergy and Clinical Immunology,...

Background The diagnostic investigation of sensitization to dust mites is performed through measurement of specific IgE and cutaneous immediate hypersensitivity tests. The general aim of this study was to comparatively evaluate the diagnostic accuracy of immediate hypersensitivity skin tests and specific IgE for Dermatophagoides pteronyssinus (Dp) and Blomia tropicalis in patients with allergic...

Dermatophagoides pteronyssinus is the European dust mite and a major source of human allergens. Here, we present the first draft genome sequence of the mite, as well as the ab initio gene prediction and functional analyses that will facilitate comparative genomic analyses with other mite species.