An unusual dermatophyte was isolated from the plantar scales of a human immunodeficiency virus-positive man with tinea pedis. Morphology, physiology, and molecular data provided evidence to support the new species Trichophyton eboreum. This dermatophyte is characterized by rapid growth on common mycological media, a flat powdery off-white colony, formation of clavate microconidia, smooth- and t...

background the treatment of onychomycosis is a challenge and infections are typically more severe and difficult to treat in toenails than in fingernails. objectives the current study aimed to investigate the fungicidal effect of ultraviolet radiation on the growth of dermatophytes isolated from nails. patients and methods samples from patients with clinical manifestations of onychomycosis were ...

Dermatophytoses Because dermatophytes require keratin for growth, they are restricted to hair, nails, and superficial skin. Thus, these fungi do not infect mucosal surfaces. Dermatophytoses are referred to as “tinea” infections. They are also named for the body site involved. Some dermatophytes are spread directly from one person to another (anthropophilic organisms). Others live in and are tra...

one of the superficial problems of public health is mycotic inflection that its incidence is not correctly known. the most important disease of them is dermatophytosis that comes through by dermatophytes as the major group of keratinophilic fungi. honey is bee product that has been used as a medicine since ancient times in many cultures, and is still used in folk medicine. this study was design...

Cutaneous mycoses are among the most common infections in humans and have become an important public health issue because they cause invasive infections in immunocompromised patients. During the infectious process, dermatophyte-host interactions trigger specific metabolic adaptations that allow the pathogen to adhere to and penetrate the host tissue, scavenge nutrients, and overcome the host de...

To determine a role of human -Defensin-2 (HBD-2) in defense against cutaneous dermatophyte infection, we investigated the induction of HBD-2 mRNA expression by a nontumorigenic human keratinocyte-derived cell line, HaCaT cells, after co-culture with microconidia collected from the colonies of Trichophyton rubrum. Co-culture of T. rubrum or Candida albicans with HaCaT cells significantly induced...

A case of dermatophytic pseudomycetoma, in a patient with a history of recurrent lesions in the scalp, for over two years, is reported. Histopathological examination of the affected tissues revealed the mycelial aggregates or pseudogranules characteristic of the disease. Cultures of fresh tissues samples detected a fungus identified as Trichophyton tonsurans. Additional examinations failed to d...