one of the challenges in the management of primary monosymptomatic enuresis (pme), especially in adolescents, is response failure to medical regimens such as desmopressin. this prospective study aimed at addressing the efficacy of sertraline in the treatment of 25 adolescents (13-18 year old) with pme having experienced failure to previous desmopressin therapy. patients were recommended to take...

PURPOSE To determine the effects of desmopressin on coagulation and blood loss in patients undergoing elective partial hepatectomy. METHODS A randomized, controlled and double-blind study on 59 patients who received either 0.3 micro g x kg(-1) of desmopressin or an equal volume of normal saline (control) infused intravenously over 20 min after induction of general anesthesia. RESULTS There ...

PURPOSE To evaluate the effectiveness of presence of desmopressin in treating primary enuresis (PE) for children with attention deficit-hyperactivity disorder (ADHD) symptoms. MATERIALS AND METHODS Children aged from 5 to 12 years with the chief complaint of PE treated with desmopressin were enrolled in pediatric urology clinics. The parent-reported SNAP-IV questionnaire was used to evaluate ...

conclusions our study showed that desmopressin could not reduce the amount of blood loss after cabg. also, desmopressin did not have a significant effect on coagulation status. therefore, based on the results of our study, it seems that the use of this medication cannot be a helpful for patients with any indication for cabg. background coronary artery bypass grafting (cabg) is a common surgical...

BACKGROUND AND PURPOSE Minimizing hematoma growth in high-risk patients is an attractive strategy to improve outcomes after intracerebral hemorrhage. We tested the hypothesis that desmopressin (DDAVP), which improves hemostasis through the release of von Willebrand factor, improves platelet activity after intracerebral hemorrhage. METHODS Patients with reduced platelet activity on point-of-ca...

BACKGROUND Patients with acute renal colic usually require immediate diagnosis and treatment. In this clinical trial analgesic effect of hyoscine N-butyl bromide and desmopressin combination in comparison with hyoscine N-butyl bromide alone in patients with acute renal colic induced by urinary stones was assessed. METHODS The study included 114 patients randomly allocated in two groups (A and...

PURPOSE The aim of this study was to evaluate the effect of desmopressin combined with anticholinergics on daytime frequency and urgency in female patients with overactive bladder (OAB). MATERIALS AND METHODS We included 68 female patients with OAB. Patients were randomly assigned to receive 5 mg of solifenacin (group I) or 5 mg of solifenacin and 0.2 mg of desmopressin (group II) for 2 weeks...

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