background: saffron (crocus satious l.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. objective: based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. methods...

A Railway Interloc king System (RIS) is an Embedded System (namely a Supervisory Control System) that ensures the safe op eration of the devic es in a R ailway Station. Of course a RIS is a Safet y Critical System. In this p aper we explore the p ossibility of integrating automatic formal veri cation methods in a given industry RIS design ow. The main obstructions to be over come in our work ar...

how to cite this article: ghofrani m. lysosomal storage disease (lsds). iran j child neurol. 2015 autumn;9:4(suppl.1): 1. pls see pdf.

background there are few reports from iran about the epidemiology and clinical features of inflammatory bowel disease (ibd). this study aims to determine the epide­miologic profile and clinical features of ibd in northwest iran referral centers. methods in a cross-sectional setting, we evaluated 200 patients with definitive diagno­ses of ibd who referred to tabriz educational hospitals during t...

conclusions in cases of unusual vascular lesions, metabolic diseases must be considered. in homocystinuria, early diagnosis and treatment are important. blood homocysteine levels can be returned to normal, and some complications can be prevented. introduction homocystinuria is a hereditary disease caused by a defect in the enzymes involved in metabolizing methionine. homocystinuria can influenc...

thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...

how to cite this article: karimzadeh p. pelizaeus-merzbacher- disease (pmd) and pelizaeus-merzbacher-like disease (pmld). iran j child neurol autumn 2014;8:4 (suppl.1):9-10.   pls see pdf.

Background: Neuromyelitis optica spectrum disorder (NMOSD) has emerged as a disorder distinct from multiple sclerosis, largely due to the discovery in 2004 of a novel disease marker, aquaporin-4 immunoglobulin or AQP4-IgG (also known as NMO-IgG). Differentiating NMOSD from multiple sclerosis has important prognostic and treatment implications. The features of pediatriconset multiple sclerosis h...

castleman’s disease (angiofollicular lymphoid hyperplasia) includes a heterogeneous group of lymphoproliferative disorders. the cause of this disease remains uncertain. there are two types of localized castleman’s disease: the more common hyaline vascular and the plasma cell types. mixed variant is an uncommon localized lesion in general population. the lesions can occur in any part of the body...