considering that mapk (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (t2dm), we have recently investigated the reported genetic polymorphism from genome wide association study in map3k1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of mapk signal...

â  â  background a substantial proportion of the mortality in patients with type 2 diabetes mellitus (t2dm) is related to non-alcoholic fatty liver disease (nafld) and its complications. insulin resistance is a major etiologic factor for the development of fatty liver. we aimed to study the prevalence of nafld among t2dm patients and its relation to insulin resistance. methods patients with t2d...

conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...

the effects of probiotic yoghurt consumption on blood pressure and serum lipids in type 2 diabetic patients: randomized clinical trial ejtahed h1, mohtadi nia j*2, homayouni rad a3, niafar m4, asghari jafarabadi m5, mofid v6 1- m.sc in nutrition science, faculty of health and nutrition, tabriz university of medical sciences, tabriz, iran. 2-*corresponding author: associate prof, dept. of food s...

type 2 diabetes mellitus (t2dm) occurs around the world with high prevalence and causes serious physical harm and economic burden to the afflicted. haikou city is china's southernmost tropical island city, which has not been previously studied for its t2dm prevalence. the objective of the study in employing a cross-sectional survey is to discuss the epidemiologic status of t2dm in haikou city a...

background : this study aimed to investigate the association of seven common inflammatory diseases with type 2 diabetes (t2d) in the chinese mainland population. methods : participants were recruited from a great swathe of mainland from 2009 to 2013 for the cohort study. the demographic characteristics between patients with t2d or with inflammatory diseases, including age, sex, smoking status, ...

there are much heterogeneity in the genetic variation of type 2 diabetes (t2d). the purpose of this study was to investigate the association of seven novel genetic loci identified in a recent genome-wide association studies (gwas) with t2d in chinese dong populations.a case-controlled study was performed in individuals of chinese dong nationality. the genotypes of pard3b (rs849230), loc729993 (...

background: transforming growth factor-beta 1(tgf-β1) t869c (rs1800470, the same below) gene polymorphism is notably relative with the development of diabetic nephropathy (dn)，and cc/ct genotype diabetic have higher frequency of than tt genotype diabetic. to find out individual risk factors in the two genotypes especially in susceptible genotype could provide more efficient and targeted prevent...

conclusions jytk combined with metformin improves some antioxidant indices (sod and mda), and decreases inflammation in patients with t2dm, suggesting that it can reduce the risk of diabetic complications. results all 112 patients, including 59 in the treatment group (jytk + metformin) and 52 controls (metformin only) completed the 26-week clinical trial. jykt plus metformin treatment increased...

conclusions mobile phone text messaging increased adherence to diabetes therapy and improved the clinical outcome in saudi patients with type 2 diabetes. results in addition to significant improvement in patients’ knowledge, mean fasting blood glucose level improved from 8.60 ± 3.16 to 7.77 ± 3.11 mmol/l and mean hba1c decreased from 9.9% ± 1.8% to 9.5% ± 1.7%. objectives we conducted a study t...