Isoprenoids are a large family of compounds with essential functions in all domains of life. Most eubacteria synthesize their isoprenoids using the methylerythritol 4-phosphate (MEP) pathway, whereas a minority uses the unrelated mevalonate pathway and only a few have both. Interestingly, Brucella abortus and some other bacteria that only use the MEP pathway lack deoxyxylulose 5-phosphate (DXP)...

This paper investigates the use of deep reinforcement learning (DRL) in the design of a “universal” MAC protocol referred to as Deep-reinforcement Learning Multiple Access (DLMA). The design framework is partially inspired by the vision of DARPA SC2, a 3-year competition whereby competitors are to come up with a clean-slate design that “best share spectrum with any network(s), in any environmen...

During development, dendrites migrate to their correct locations in response to environmental cues. The mechanisms of dendritic guidance are poorly understood. Recent work has shown that the Drosophila olfactory map is initially formed by the spatial segregation of the projection neuron (PN) dendrites in the developing antennal lobe (AL). We report here that between 16 and 30 h after puparium f...

Artificially intelligent agents equipped with strategic skills that can negotiate during their interactions with other natural or artificial agents are still underdeveloped. This paper describes a successful application of Deep Reinforcement Learning (DRL) for training intelligent agents with strategic conversational skills, in a situated dialogue setting. Previous studies have modelled the beh...

This paper investigates exploration strategies of Deep Reinforcement Learning (DRL) methods to learn navigation policies for mobile robots. In particular, we augment the normal external reward for training DRL algorithms with intrinsic reward signals measured by curiosity. We test our approach in a mapless navigation setting, where the autonomous agent is required to navigate without the occupa...

EasyMiner (easyminer.eu) is a web-based association rule mining software based on the LISp-Miner system. This paper presents a proof-of-concept workflow for learning business rules with EasyMiner from transactional data. The approved rules are exported to the Drools business rules engine in the DRL format. The main focus is the transformation of GUHA association rules to DRL.

In recent years a number of the genes that regulate muscle formation and maintenance in higher organisms have been identified. Studies employing invertebrate and vertebrate model organisms have revealed that many of the genes required for early mesoderm specification are highly conserved throughout evolution. Less is known about the molecules that mediate the steps subsequent to myogenesis, e. ...