OBJECTIVE The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS A consecutive series of 935 diabetic patients treated with oral agents and/or insulin were followed for 1 year after PT...

1 Université Paris 6, UFR de Médecine, Paris, France; AP-HP, Hôpital Tenon, Département de Santé Publique, Paris, France; Université Paris 13, UFR SMBH, LIM&BIO, Bobigny, France; APREC, Paris, France. 2 AP-HP, DSI, STIM, Paris, France; INSERM, UMR S 872, eq. 20, Paris, France. 3 AP-HP, HEGP, Service de Médecine Vasculaire et Hypertension Artérielle, Paris, France. 4 SFTG, Paris, France; Univers...

inabilities to attain adequate aqueous solubility and stability have made the preparation of a clinically suitable formulation of taxol difficult. addition of nicotinamide (nd), 2-hydroxypropyl- b-cyclodextrin (hpßcd), polyethylene glycol, (peg), bile salts (bs, 50:50 sodium cholate: deoxycholate), and cremophor el can improve the solubility of taxol. studies were undertaken to compare the stab...

BACKGROUND Serum haptoglobin (Hp) is a reliable marker for hemolysis regardless the inflammatory state. OBJECTIVE We investigated the possible relation between Hp depletion and hemolysis severity, hepatitis C virus (HCV) infection and iron load in β-thalassemia children. METHODS Twenty two β-thalassemia major (TM),20 β-thalassemia intermedia (TI) children with 20 age and sex matched healthy...

Background: The high protein (HP) breakfast reduced gastric emptying and the most satiating macronutrient appears to be dietary protein. Few studies have investigated the effects of protein to energy ratio in breakfast on mood, alertness and attention. Objective: This study was designed to investigate whether the HP breakfast is more beneficial to mood, alertness and attention of the healthy un...

BACKGROUND Sarcopenia is associated with adverse outcomes such as physical disability, poorer quality of life, and death. Helicobacter pylori (HP) eradication increases ghrelin secretion, which may be a possible treatment for sarcopenia. We investigated whether HP eradication reduces the risk of low muscle mass (LMM), which is an integral component of sarcopenia. MATERIALS AND METHODS Healthy...

In humans, early high protein (HP) intake has been recommended to prevent postnatal growth restriction and complications of intrauterine growth restriction (IUGR). However, the impact of such a strategy on the kidneys remains unknown, while significant renal hypertrophy, proteinuria, and glomerular sclerosis have been demonstrated in few experimental studies. The objective of this study was to ...

OBJECTIVE To measure the urinary excretion of specific cross-link amino acid markers for mature elastin (desmosine [DES] and isodesmosine [IDES]) and fibrillar collagen (hydroxylysylpyridinoline [HP] and lysylpyridinoline [LP]) in systemic sclerosis (SSc) patients and healthy controls. METHODS Urine specimens from 20 patients with SSc and 22 controls were assessed for DES, IDES, HP, and LP us...

Background: Triple therapy with a proton pump inhibitor and two antibiotics in Helicobacter pylori (HP) eradication is widely accepted, but this combination fails in a considerable number of cases. The aim of this study was to assess the effect of clidinium-C addition on HP eradication and to investigate the efficacy and safety of clidinium-C in prevention of drugs' side effects. Methods: A ...

Forty-eight tumor-free mice and 32 mice bearing Ehrlich ascites tumor were randomized into 2 treatments, Acinetobacter glutaminase-asparaginase (AGA) (600 IU/kg/day for 7 days) and 0.9% NaCl controls, and into 2 or 3 isocaloric diets, normal protein (NP) (20 g protein/100 g diet), high protein (HP) (58 g protein/100 g diet), and zero protein (ZP) (tumor-free mice only). In tumor-free, NP-fed mi...