Simple, precise and economic batch flow injection analysis (FIA)-spectrophotometric methods have been established for simultaneous determination of salbutamol sulfate (SLB) in bulk powder pharmaceutical forms. Both based on diazotization coupling reaction SLB with another drug compound (sulfadimidine) as a safe green agent alkaline medium. At 444 nm, the maximum absorption orange azo-dye produc...

Diazotization of p-toluidine and coupling with 3-amino-phenol-Formaldehyde (APF) resin give oligomaric azo dye TAPF, based on 3-amino-phenol-Formaldehyde (APF) polymer. The TAPF was then treated with 5-chloro methyl-8quinolinol hydrochloride in the presence of a THF in alkaline medium (pH 9-10) at room temperature for 7 hrs. The resultant oligomaric ligand designated as azo polyphenol-formaldeh...

A novel gas sensor consisting of porous, non-stacked reduced graphene oxide (NSrGO)-heaxfluorohydoroxypropanyl benzene (HFHPB) nanosheets was successfully fabricated, allowing the detection of dimethyl methyl phosphonate (DMMP), similar to sarin toxic gas. The HFHPB group was chemically grafted to the NSrGO via a diazotization reaction to produce NSrGO-HFHPB. The NSrGO-HFHPB 3D film has a mesop...

A new sensitive colorimetric method for determination of ascorbic acid tablet in aqueous solution. The method is based on the formation of colored azo dye by diazotization of 2, 4dichloroaniline followed by azo-coupling reaction between the resulting product and ascorbic acid. The optimum conditions that gave maximum absorption of azo dye at535nm, with best concentration of reactant and order o...

A photoluminescent detection method for nitrite with high selectivity and sensitivity using carbon nanodots (CNDs) is demonstrated. The selectivity of nitrite is accomplished by a highly specific diazotization reaction between nitrite and p-phenylenediamine (p-PDA). In the presence of nitrite, p-PDA easily reacts to form the diazonium cation in the acidic aqueous solution. By alkalization of th...

A method is reported for determining urinary xanthenuric acid (XA), a meta. bolite of tryptophan. XA is extracted from urine with isobutanol (2.methyl. 1.propanol), transferred to ammonium hydroxide, and separated from other urinary metabolites on thin.Iayer cellulose plates with use of 0.2 acetate buffer, mol/liter, pH 5.4. The XA is measured spectrophotometrically after diazotization with 2-c...

1. Azopigments derived from conjugated bile pigments by coupling with the diazonium salt of ethyl anthranilate are analysed conveniently by quantitative t.l.c. or by column chromatography on CM-cellulose. 2. By chromatographic studies combined with a series of chemical tests six groups of azopigments were demonstrable in preparations from bile and from icteric urine of man. Azobilirubin and its...

the composite diazotization coupling reaction of sulfanilic acid and n, ndimethylaniline was used for the precise, accurate, and rapid determination of trace amounts of nitrite ion (0.02-3 µg/ml). the reaction was monitored spectrophotometrically by measuring the absorbance of the produced methyl orange at 510 nm by a fixed the method of 5.0 minutes. the relative standard deviation for the dete...

five new 1-hydroxy-2-(1-alkyloxymethyl)-9,10-anthraquinones (9a-e) have been prepared. selective nitration of 2-methyl-9,10-anthraquinone, reduction to the corresponding amine, diazotization and treatment by sulfuric acid solution afforded the 1-hydroxy-2-methyl-9,10-anthraquinone in good yield as the key intermediate. reaction with dimethylsulphate/k2co3 and subsequent monobromination with nbs...

INTRODUCTION The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) results in the formation of a precipitate. In a previous study, we demonstrated the formation of 4-chloraniline (PCA) in the precipitate in an amount directly related to the concentration of NaOCl used. AIMS AND METHODS The aim of the present study was to use a diazotization technique to confirm the presence o...