conclusions although we found an association between myh9 gene polymorphism and urinary albumin excretion, the results did not show a significant association between myh9 polymorphism (rs4821481) and risk of dn in iranian diabetic patients. background myosin heavy chain 9 (myh9) gene polymorphisms have been implicated in different types of renal disease, as well as in nephropathy attributed to ...

Interleukin-7 receptor (IL-7R) levels are tightly controlled during ontogeny: high on double-negative (DN) cells, absent on double-positive (DP) cells, and high once again on thymocytes undergoing positive selection. To determine if loss of IL-7-mediated survival signals in DP cells is necessary for normal antigen-specific selection, we created T-lineage-specific IL-7R alpha chain (IL-7Ralpha) ...

Background: The role of attenuation in antioxidant capacity or expansion of pro-oxidant/oxidant is well known for the development of stress oxidative. The aim of this study was to evaluate the plasma antioxidant capacity along with uric acid in patients with diabetic nephropathy (DN+) and without diabetic nephropathy (DN-). Materials and Methods: The research population included 88 patients ...

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. The use of experimental models of DN has provided valuable information regarding many aspects of DN, including pathophysiology, progression, implicated genes, and new therapeutic strategies. A large number of mouse models of diabetes have been identified and their kidney disease was characterized to various degrees. Most...

Let S be a Borel subset of Polish space and F the set bounded functions f:S→R. an(·)=P(Xn+1∈·∣X1,…,Xn) n-th predictive distribution corresponding to sequence (Xn) S-valued random variables. If is conditionally identically distributed, there probability measure μ on such that ∫fdan⟶a.s.∫fdμ for all f∈F. Define Dn(f)=dn∫fdan−∫fdμ f∈F, where dn>0 constant. In this note, it shown that, under som...

Methods that infer site-specific dN/dS, the ratio of nonsynonymous to synonymous substitution rates, from coding data have been developed primarily to identify positively selected sites (dN/dS > 1). As a consequence, it is largely unknown how well different inference methods can infer dN/dS point estimates at individual sites. In particular, dN/dS may be estimated using either a one-rate approa...

D-branes can end on orbifold planes if the action of the orbifold group includes (−1)FL . We consider configurations of D-branes ending on such orbifolds and study the low-energy theory on their worldvolume. We apply our results to gauge theories with eight supercharges in three and four dimensions. We explain how mirror symmetry for N = 4 d = 3 gauge theories with gauge group Sp(k) and matter ...

INTRODUCTION St. Thomas' cardioplegic solution No. 2 (ST), although most widely used in adult cardiac surgery, needs to be given at short intervals, causing additional myocardial injury. AIM To determine whether del Nido (DN) cardioplegia, with longer periods of arrest, provides equivalent myocardial protection as compared to ST. MATERIAL AND METHODS The study population comprised 100 patie...