Background—Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of PPCM are part of the spectrum of familial DCM, presenting in the peripartum period. Methods and R...

Background—Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of PPCM are part of the spectrum of familial DCM, presenting in the peripartum period. Methods and R...

BACKGROUND Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of PPCM are part of the spectrum of familial DCM, presenting in the peripartum period. METHODS AND...

ilated cardiomyopathy (DCM), characterized by left venricular dilation and systolic dysfunction, is the most comon form of heart muscle disease, comprising 60% of the ases of identified cardiomyopathies (1). The disorder is linically heterogeneous, ranging from affected individuals ith clinical presentations of severe symptoms, including eart failure, sudden death, or resuscitated sudden death,...

Dynamic Concept Model (DCM) of more distinctions allowing faster convergence and is a goal-oriellted neural controller, that builds generalization [2]. an internal representation of events and chains of events in the form of a directed graph and uses spreading activation for decision making [1]. It is shown, that a special case of DCM is equivalent to reinforcement learning (RL) and is capable ...

AIMS The mutations most frequently associated with dilated cardiomyopathy (DCM) have been reported in the lamin A/C gene. The role of variants of the lamin A/C gene was investigated in patients with DCM from eastern and southern Finland. METHODS AND RESULTS All 12 exons of the lamin A/C gene were screened in 18 well-characterised familial DCM patients from eastern and southern Finland and in ...

BACKGROUND The presence of apoptotic myocytes has been reported in human hearts with dilated cardiomyopathy (DCM) on the basis of a positive finding of DNA in situ nick end-labeling (TUNEL). However, ultrastructural evidence of myocyte apoptosis has not been obtained. METHODS AND RESULTS A total of 80 endomyocardial biopsies were obtained from right and left ventricles of 20 patients with DCM...

This paper discusses the diachronic development of non-structural case marking in TibetoBurman and in computer simulations of language evolution. It is shown how case marking is initially motivated by the pragmatic need to disambiguate between two core arguments, but eventually may develop flagging functions that even extend into the intransitive domain. Also, it is shown how different types of...

The examples in (1) and (2) exemplify what I will call PSEUDOPARTITIVES in Estonian. (1) hargi-täisN1 pitchfork-ful põhkuN2 straw.PAR ‘a/the pitchforkful of straw’ (EKSS, entry for hargitäis) (2) parvN1 flock pääsukesiN2 swallow.PL.PAR ‘a/the flock of swallows’ (Nemvalts, 1996:69) Key aspects of the pseudopartitive construction: • One noun (N1) serves a quantifying or measuring role (broadly sp...

ion Level Link type Possible direction(s) of traversal (Inter-level) IsAllocatedTo both Satisfies both Abstraction (without subtypes) both Implements both Requirements ConflictsWith none Constrains source← target DependsOn source→ target DerivesFrom source→ target Elaborates source→ target IsSimilarTo both MakesPossible source← target Operationalizes source← target Fulfils both InvocationRelati...