BACKGROUND Lamina-associated polypeptides 2 (LAP2) is a nuclear protein that connects the nuclear lamina with chromatin. Although its critical roles in genetic disorders and hematopoietic malignancies have been described, its expression and roles in digestive tract cancers have been poorly characterized. METHODS To examine the expression of LAP2 in patient tissues, we performed immunohistoche...

This study was conducted to examine the effects of dietary cellulose levels on growth, nitrogen utilization, the retention time of diets in the digestive tract, and caecal microflora of 2-month-old Single Comb White Leghorn male chickens fed 3 purified diets that contained 0, 3.5% and 10% cellulose in equal amount of nutrients for 7 days. Body weight gain and nitrogen utilization were significa...

Bile acids (BAs) are not only digestive surfactants but also important cell signaling molecules, which stimulate several signaling pathways to regulate some important biological processes. The bile-acid-activated nuclear receptor, farnesoid X receptor (FXR), plays a pivotal role in regulating bile acid, lipid and glucose homeostasis as well as in regulating the inflammatory responses, barrier f...

The aim of the present work is clarifying the ontogeny of the Egyptian Sole digestive system during its larval stage (0DAH, day after hatching) until it become a juvenile (40DAH). The main changes in the morphological digestive tract was detected during its early life at 2DAH (both the mouth and anus are opened). Another day after, the digestive tract of S. vulgaris became longer. After metamor...

The ontogeny of the digestive tract was studied histologically in burbot, Lota lota L., from hatching to 42 days post-hatch (dph). At hatching, the digestive tract consisted of a straight tube with discernible digestive accessory glands (the liver and the pancreas) dorsally attached to the yolk sac. Most of the yolk sac reserves were consumed during the first 12 days and were completely deplete...

OBJECTIVE To analyse various aspects of the Mediterranean diet in relation to the risk of several common cancers in Italy. DESIGN Data from a series of case-control studies conducted in northern Italy between 1983 and 2004 on over 20,000 cases of several major cancers and 18,000 controls. RESULTS For most digestive tract cancers, the risk decreased with increasing vegetable and fruit consum...