S100B is a calcium binding peptide produced predominantly by astroglial cells in the central nervous system. S100B paradoxically has neurotrophic and apoptotic effects, dependent on extracellular concentration. This study investigated the relationship between serum S100B levels and neuropsychological performance across a range of cognitive domains in healthy older aged adults. A cohort of 219 p...

Background: Cognitive impairment profoundly influences on older adults’ activities and quality of life. Therefore, optimizing and remediating age-associated cognitive decline have great importance. Objectives: To evaluate the effect of 8 weeks (3 day /week) computer based brain training on cognitive performance in old women with Mild Cognitive Impairment (MCI). Materials and Methods...

OBJECTIVE We report preliminary findings on the efficacy of interactive metronome (IM) therapy for the remediation of cognitive difficulties in soldiers with persisting cognitive complaints following blast-related mild-to-moderate traumatic brain injury (TBI). METHOD Forty-six of a planned sample of 50 active duty soldiers with persistent cognitive complaints following a documented history of...

Iron deficiency and anaemia affect millions of children worldwide. This study aimed to investigate the effect of iron deficiency with or without anaemia on cognitive functions, specifically with short-term memory, attention and visual motor coordination in children. A total of 173 primary school children was enrolled. Cognitive functions were assessed using the Wechsler Intelligence Scale for C...

We investigated the relation between cognitive processing speed and structural properties of white matter pathways via convergent imaging studies in healthy and brain-injured groups. Voxel-based morphometry (VBM) was applied to diffusion tensor imaging data from thirty-nine young healthy subjects in order to investigate the relation between processing speed, as assessed with the Digit-Symbol su...

The Symbol Digit Modalities Test (SDMT) is commonly used to evaluate an individual's switching attention and processing speed. However, its test-retest reliability and practice effect are not well known in patients with stroke, limiting its utility in both clinical and research settings. The present study examined the two aforementioned psychometric properties of the oral-format SDMT on a group...

To date there are very few laboratory data available regarding the long-term effect of the psychostimulant khat on human neurocognitive functioning. The purpose of the present study was to assess whether chronic khat users would demonstrate impairments in working memory and speed of information processing compared to control subjects. Working memory was assessed using the forward and backward d...

BACKGROUND Using conscious subjects, measurement of the effects of low concentrations of anaesthetic agents can allow the dynamics of onset and offset of the agent to be measured and kinetic values estimated. However, the tests have to be rapid and preferably assess cerebral function. METHODS We used a short version of the digit symbol substitution test (DSST) that allowed frequent measuremen...

Submit Manuscript | http://medcraveonline.com Abbreviations: mTBI: Mild Traumatic Brain Injury; AIB: The American Institute of Balance; VCI: Vestibular Cognitive Integration; PC-BPPV: Posterior Canal Benign Paroxysmal Positional Vertigo; GSOP: Gans Sensory Organizational Performance Test; VR: Vestibular Rehabilitation; BPM: Beats Per Minute; NAB: Neuropsychological Assessment Battery; HVLT: Hop...