Idiopathic dilated cardiomyopathy is a primary myocardial disease with unknown aetiology. This disease follows a prospective course that is characterized by ventricular dilation and impaired myocardial dilation. Congestive heart failure and malignant arrhythmias are the most widespread complications. The incidence of idiopathic dilated cardiomyopathy in the general population is 5-8/100.000. Be...

left ventricular non-compaction cardiomyopathy is a rare congenital cardiomyopathy that affects both children and adults. since the clinical manifestations are not sufficient to establish diagnosis, echocardiography is the diagnostic tool that makes it possible to document ventricular non-compaction and establish prognostic factors. we report a 47-year-old woman with a history of dilated cardio...

Definition and Classification The cardiomyopathies are a diverse group of myocardial diseases that are characterized by chronic ventricular dysfunction. The clinical classification of cardiomyopathy is based on hemodynamic and echocardiographic abnormalities, and consists of dilated cardiomyopathy, hypertrophic cardiomyopathy, and restrictive cardiomyopathy. Recently, arrhythmogenic right ventr...

Objective: In dilated cardiomyopathy and in athlete’s heart, progressive LV dilatation is accompanied by rightward displacement of thediastolic LV pressure–volume relation. In dilated cardiomyopathy, an increase in diastolic LV stiffness can limit this rightwarddisplacement thereby decreasing LV systolic performance. Because nitric oxide (NO) reduces diastolic LV stiffness, the present ...

BACKGROUND Idiopathic dilated cardiomyopathy is a familial disorder in 25% to 50% of patients, but the genetic basis in the majority of cases remains unknown. Genes encoding desmosomal proteins, currently regarded as synonymous with another disorder, arrhythmogenic right ventricular cardiomyopathy, are known to cause left ventricular dysfunction, but their importance in unselected patients with...

Although idiopathic cardiomyopathies are prognostically important and are a common indication for cardiac transplantation in all age groups, the incidence and age distribution of idiopathic cardiomyopathies in a well-defined pediatric population have been poorly characterized. A retrospective study was carried out in Finland in 1980-1991 to obtain information on the epidemiology of childhood ca...

BACKGROUND In Dilated cardiomyopathy the heart is enlarged and ventricles are dilated. Gated myocardial perfusion single photon emission computed tomography is considered state of the art for myocardial perfusion imaging. A retrospective analysis was conducted to evaluate patients with dilated cardiomyopathy with Tc-99m sestamibi gated myocardial perfusion single photon emission computed tomogr...

Cardiomyopathy is often found in patients with Duchenne and Becker muscular dystrophy, which are X linked muscle diseases caused by mutations in the dystrophin gene. Dystrophin defects present in many different ways and cases of mild Becker muscular dystrophy have been described in which cardiomyopathy was severe. Female carriers of Duchenne muscular dystrophy can develop symptomatic skeletal m...

Dilated cardiomyopathy is one of the most common causes of the heart failure in childhood and can develop as a consequence of metabolic disorders such as fatty acid beta-oxidation disorders or amino acids metabolism disorders. In our report we present a case where in the course of deficiency of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase the recovery from dilated cardiomyopathy resulted i...

We report about an infant affected by dilated cardiomyopathy (CMP) in whom metabolic investigations evidenced medium-chain-acyl-CoA dehydrogenase deficiency (MCADD), that is one of three types of inherited disorders of mitochondrial fatty-acid beta-oxidation. Long-chain and very long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficits are recognized as responsible of hypertrophic or, less fre...