BACKGROUND 3,3'-Diindolylmethane (DIM) is a condensation product of indole-3-carbinol, a glucosinolate naturally occurring in Brassica genus vegetables. The antiinflammatory properties of DIM through the inhibition of NF-κB, as well as its ameliorating effects on glucose tolerance and hyperglicemic states, have been described. A subclinical proinflammatory profile resultant from the interaction...

1. Introduction. In recent years more and more attention has been paid in mathematical papers to fractal functions and to fractal sets. There are various definitions of those objects. We assume that a compact set K ∈ R d+1 is fractal, by definition, if its box (entropy) dimension dim b (K) = j for j = 0, 1,. .. , d + 1 and 0 < dim b (K) < d + 1. At the same time the function f : I d → R d , I =...

3. Experimental methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303 3.1. Multiple-quantum filters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 303 3.2. Selection rules . . . . . . . . . ...

http://www.sciencemag.org/cgi/content/full/307/5712/1072 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/307/5712/1072/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http:/...

http://www.sciencemag.org/cgi/content/full/307/5717/1955 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/307/5717/1955/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http:/...

Indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM) are naturally occurring dietary components found in cruciferous vegetables. In the stomach, I3C forms condensation products including DIM. I3C and DIM are marketed as dietary supplements, but little is known about the safety of long-term exposure. Rats were fed either control diet, 1 or 10x the current human dose of absorption-enhanced DIM...

1 The Borsuk-Ulam theorem We have seen how combinatorics borrows from probability theory. Another area which has been very beneficial to combinatorics, perhaps even more surprisingly, is topology. We have already seen Brouwer's fixed point theorem and its combinatorial proof. Theorem 1 (Brouwer). For any continuous function f : B n → B n , there is a point x ∈ B n such that f (x) = x. A more po...