The sulfonamidohelicene tetramer changes its structure between a random-coil and a helix-dimer, by which molecular thermal hysteresis appears. Mixing experiments on helix-dimer and random-coil solutions and kinetic analysis show that the transition from the random-coil to the helix-dimer involves self-catalysis by the helix-dimer.

Results: The incidence of AKI was 23.2%.  AKI had significant correlation with older age (p-value 0.006) and hypertension (p-value 0.034) . Chest pain and abdominal pain were more common in patients with than those without AKI. Also Mean serum concentration of inflammatory markers ( D-dimer and C-reactive protein (CRP)) in patients with AKI was 1863.6±1599 ng/ml and 66.65±60.81 ng/ml, compared ...

BACKGROUND Higher plasma D-dimer levels are strong predictors of mortality in HIV+ individuals. The factors associated with D-dimer levels during HIV infection, however, remain poorly understood. METHODS In this cross-sectional study, participants in three randomized controlled trials with measured D-dimer levels were included (N = 9,848). Factors associated with D-dimer were identified by li...

The purpose of the present study was to evaluate the effects of enoxaparin (ENO) and fondaparinux (FPX) on postoperative plasma D-dimer levels and risk factors associated with postoperative venous thromboembolism (VTE) and pulmonary thromboembolism (PTE) in patients with gynecologic cancer. For this study, 434 patients with gynecologic cancer were recruited and a surgical treatment strategy was...

STUDY OBJECTIVES The aim of this study was to investigate the prognostic value of plasma d-dimer levels in patients with community-acquired pneumonia (CAP). DESIGN Prospective observational study. SETTING Hospital Lluis Alcanyis of Xativa, Spain. PATIENTS Consecutive adult patients admitted to the hospital with CAP from January 2000 to October 2002. MEASUREMENTS AND RESULTS A total of 3...

Acute aortic dissection is a rare but devastating condition with high mortality. Unfortunately, there is no sensitive screening indicator of disease in common use. The objective of this study was to assess the sensitivity and utility of the serum D-dimer as a test for acute aortic dissection. A pooled analysis was performed of all original research studies testing the sensitivity of serum D-dim...

The near-infrared and visible wavelength spectrum of the water dimer is considered to be the major contributor to the so-called water continuum at these wavelengths. However, theoretical models of this spectrum require the simultaneous treatment of both monomer and dimer excitations. A model for treating this problem is proposed which is based upon a Franck–Condon-like separation between the mo...

PURPOSE The relationship between plasma D-dimer level and the prognosis of advanced non-small-cell lung cancer (NSCLC) is not well studied. This study investigated the role of plasma D-dimer as a prognostic factor in advanced NSCLC. METHODS The plasma D-dimer was measured in 1,931 newly diagnosed advanced NSCLC patients by enzyme-linked immunosorbent assay. Correlations between plasma D-dimer...

Cyclocondensation between 4,4`-bis(4-chlorobenzenesulfonyl)biphenyl and catechol, with subsequent chromatographic separation of the reaction products, led to isolation four novel ether-sulfone macrocycles (cyclic dimer, -trimer, -tetramer -pentamer). Similarly, cyclocondensation catechol a seven-ring diketone/disulfone monomer allowed two new aromatic ether-ketone-sulfone macrocycles, cyclic di...

BACKGROUND Little is known about the diagnostic value of a D-dimer test in cancer patients with clinically suspected deep venous thrombosis (DVT). OBJECTIVE To evaluate the clinical utility of a whole blood rapid D-dimer test (SimpliRED) in cancer patients compared with noncancer patients. METHODS In consecutive patients with suspected lower limb DVT, a D-dimer test and ultrasonogram were p...