In listwise directed forgetting, participants are cued to forget previously studied material and to learn new material instead. Such cueing typically leads to forgetting of the first set of material and to memory enhancement of the second. The present study examined the role of working memory capacity in adults' and children's listwise directed forgetting. Working memory capacity was assessed w...

The role of inhibition in children's (5-, 7-, and 11-year-olds') false memory illusions in the Deese-Roediger-McDermott (DRM) paradigm was examined using a list-wise directed-forgetting procedure. Children studied either a single DRM list (control) or two DRM lists in succession with a directed-remembering instruction or a directed-forgetting instruction between list presentations. The findings...

Episodic forgetting can arise in a number of different situations. Recall of target material can be impaired if additional material is learned (interference), related information is repeatedly retrieved (retrieval-induced forgetting), or an instruction to intentionally forget the target material is provided (directed forgetting). The question arises which mechanisms underlie these different for...

background tyrosinase, as a copper-containing enzyme, is widely distributed in different levels of life span. it is also a key enzyme in melanin biosynthesis, which plays a crucial role in determining the color of mammalian skin and hair. objectives the current study aimed to determine the effect of a palladium complex on cresolase and catecholase reactions of mushroom tyrosinase (mt). material...

In a directed forgetting task, midway through presentation of the list, participants are instructed to forget the first half of the list and to remember the second half of the list. Memory is tested for both to-beforgotten (TBF) and to-be-remembered (TBR) words. Typically, participants recall TBR more often than TBF words, although they remember just as many TBF as TBR words on recognition test...

epigenetics alterations, especially dna methylation, play a critical role in control of gene expressions. abnormal patterns of methylation are observed in early-stages of many cancers. therefore, methylation analysis is useful in primary detection of tumors. advances knowledge about the functional role of aberrant epigenetic modifications as potential biomarkers for cancer, have attracted consi...

Invasive melanoma is projected to become the second-most common cancer in US and most men by 2030. NRAS-mutant melanomas are subtype lacking effective molecularly targeted therapies. Multiple synthetic lethal screens have identified SHOC2 as an essential cooperator with oncogenic RAS. Previous data from our group shown that RAS activates MAPK signaling forming a trimeric complex PP1C, crystal s...