UNLABELLED OBJECTIVE To systematically review the methodology of general burden of disease studies. Three key questions were addressed: 1) what was the quality of the data, 2) which methodological choices were made to calculate disability adjusted life years (DALYs), and 3) were uncertainty and risk factor analyses performed? Furthermore, DALY outcomes of the included studies were compared. ...

BACKGROUND This study attempted to measure the environmental burden of disease by examining mortality and disability rates in South Korea, permitting international comparisons. METHODS Disability-adjusted life years (DALY) was used to analyze data from public records. Years of life lost (YLL) and years lost to disability (YLD) were measured in terms of incidence rate and number of deaths. Att...

BACKGROUND South Africa is experiencing epidemiological transition, with the burden of chronic diseases increasing. Stroke is currently the second leading cause of death in South Africa; however, limited data are available on incidence, prevalence and resulting disability. Quantifying the epidemiological parameters and disease burden is important in the planning of health services. AIMS To sy...

BACKGROUND To estimate the disability-adjusted life years (DALY) in a nationwide representative sample of postmenopausal women with osteoporosis. The effects of drug-based therapy and risk factors for osteoporotic bone fractures on DALY losses were also explored. METHODS DALY were estimated based on participant's clinical characteristics and Health-Related Quality-of-Life (HRQoL) data obtaine...

BACKGROUND Viral hepatitis is a major health problem in Brazil and worldwide. The state of Santa Catarina has high endemic areas, and the disease burden is unknown. OBJECTIVES To estimate and analyze the burden of hepatitis B in the state of Santa Catarina, in 2005 - 2010. MATERIALS AND METHODS A time-series analysis was conducted using notification data of incidence and mortality rates fro...

BACKGROUND There is an increasing body of published cost-utility analyses of health interventions which we sought to draw together to inform research and policy. METHODS To achieve consistency in costing base and policy context, study scope was limited to Australian-based cost-effectiveness analyses. Through a comprehensive literature review we identified 245 health care interventions that me...

BACKGROUND Examining life expectancy and general mortality rates, the health of the population of Geneva can be described as one of the best in the world. However, in some areas Geneva fares worse than the rest of Switzerland or Europe. To re-appraise the current health priorities of the Genevan population, we analysed the relative importance of specific diseases and injuries calculating DALYs....

El Salvador 135 383 61 031 67 867 23 890 26 566 376.78 418.99 Puerto Rico 28 619 12 901 14 347 5050 5616 148.23 164.83 Colombia 83 832 37 791 42 025 14 793 16 450 30.61 34.04 Guatemala 22 057 9943 11 057 3892 4328 25.16 27.98 Venezuela 37 015 16 686 18 556 6532 7263 21.48 23.89 Nicaragua 3556 1603 1783 627 698 10.32 11.48 Honduras 4086 1842 2048 721 802 8.90 9.90 Costa Rica 238 107 119 42 47 0....