PURPOSE This study aimed to develop a machine learning-based algorithm for objective classification of the optic disc in patients with open-angle glaucoma (OAG), using quantitative parameters obtained from ophthalmic examination instruments. METHODS This study enrolled 163 eyes of 105 OAG patients (age: 62.3 ± 12.6, mean deviation of Humphrey field analyzer: -8.9 ± 7.5 dB). The eyes were clas...

A new method for automatic optic disc localization and segmentation is presented. The localization procedure combines vascular and brightness information to provide the best estimate of the optic disc center which is the starting point for the segmentation algorithm. A detection rate of 99.58% and 100% was achieved for the Messidor and ONHSD databases, respectively. A simple circular approximat...

This paper gives an overview of the UK network RIDERS – Research in Interactive Drama Environments, Role-Play and Story-telling, running for 36 months from September 2011. It discusses the three central themes of RIDERS: theoretical work on the conflict between interactivity and narrative content, problems, issues and tools relating to authoring, and directions in evaluation. It gives a brief o...

Treatment procedures for anterior disc displacement (ADD) of temporomandibular joint (TMJ) are far from reaching a consensus. The aim of the study was to evaluate disc status changes of anterior disc displacement with reduction (ADDWR) and without reduction (ADDWoR) comparatively, to get a better understanding of the disease progress without intervention. This longitudinal retrospective study i...

even though intervertebral disc degeneration can be found in the natural course of alkaptonuria, detection of the disease by black disc color change in a patient without any other presentation of alkaptonuria is an exceptionally rare condition. we have reported a very rare case of alkaptonuria presented with low back pain and steppage gait in a 51-year-old male with a complaint of chronic low-b...

Diskoseismic c-modes in accretion discs have been invoked to explain low-frequency variabilities observed in black-hole X-ray binaries. These modes are trapped in the inner-most region of the disc and have frequencies much lower than the rotation frequency at the disc inner radius. We show that because the trapped waves can tunnel through the evanescent barrier to the corotational wave zone, th...

We examine two corollaries of MOND pertaining to properties of the equivalent darkmatter halo. MOND predicts for pure exponential discs a tight relation involving the halo and disc scale lengths and the mean acceleration in the disc, which we find to test favorably against the Verheijen sample of Ursa Major galaxies. A correlation between halo and disc length scales is also apparent when the “m...

OBJECTIVE To determine the prevalence of extended spectrum b-lactamase at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia and to compare the ability of the disc diffusion, double disc potentiation methods and the extended-spectrum b-lactamase E test to detect exended-spectrum b-lactamase among enterobacteriaceae. METHODS This study was undertaken during the time period period...

Resistance by virtue of production of ESBL in gram negative bacteria is an emerging problem leading to therapeutic failure when β-lactam drugs are used. However, their presence may be missed while using routine disc diffusion methods for antibiotic susceptibility testing. All isolates of E. coli, K. pneumoniae, K. oxytoca and P. mirabilis were studied for ESBL production by CLSI recommended Phe...

We report a rare case of optic nerve atrophy with severe disc cupping resulting from methanol poisoning. A 30-year-old man presented to the hospital complaining of decreased visual acuity in both eyes a day after drinking alcohol containing methanol. His initial visual acuity allowed for only visualizing hand motion and not corrected in either eye. Initial intraocular pressure was within normal...