نتایج جستجو برای: disseminated leishmaniasis

تعداد نتایج: 36981  

Journal: :Acta Tropica 2021

Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of the genus Leishmania. It major health problem in many tropical and subtropical regions world can produce three different clinical manifestations, among which cutaneous leishmaniasis has higher incidence than other forms. There are no recognized reliable means chemoprophylaxis or vaccination against infections with f...

2017
Mohammad Moafi Hossein Rezvan Roya Sherkat Roya Taleban Ali Asilian Seyed Hamid Zarkesh Esfahani Mohammad Ali Nilforoushzadeh Fariba Jaffary Awat Feizi

INTRODUCTION Seldom cutaneous leishmaniasis (CL) may present as a lasting and active lesion(s), known as a non-healing form of CL (NHCL). Non-functional type 1 T helper (Th1) cells are assumed the most important factor in the outcome of the disease. The present study aims to assess some molecular defects that potentially contribute to Th1 impairment in NHCL. METHODS AND ANALYSIS This prospect...

Journal: :Journal of immunology 2015
Pablo R S Oliveira Hélia Dessein Audrey Romano Sandrine Cabantous Maria E F de Brito Ferrucio Santoro Maira G R Pitta Valéria Pereira Lain C Pontes-de-Carvalho Virmondes Rodrigues Sima Rafati Laurent Argiro Alain J Dessein

The outcome of Leishmania infections varies substantially, depending on the host and the parasite strain; infection may be asymptomatic or cause mild or severe skin ulcers (cutaneous leishmaniasis [CL]), limited or disseminated lesions, or lethal visceral disease. We previously reported an association between IL-2R mutations and susceptibility to visceral leishmaniasis in children infected with...

2014
Ana Luiza Grizzo Peres Martins Jaison Antonio Barreto José Roberto Pereira Lauris Ana Claudia Grizzo Peres Martins

BACKGROUND American tegumentary leishmaniasis has an annual incidence of 1 to 1.5 million cases. In some cases, the patient's immune response can eliminate the parasite, and the lesion spontaneously resolves. However, when this does not occur, patients develop the disseminated form of the disease. OBJECTIVE To investigate the association between clinical, laboratory and pathological findings ...

2011
Veeranoot Nissapatorn Nongyao Sawangjaroen

After 30 years of the human immunodeficiency virus (HIV) epidemic, parasites have been one of the most common opportunistic infections (OIs) and one of the most frequent causes of morbidity and mortality associated with HIV-infected patients. Due to severe immunosuppression, enteric parasitic pathogens in general are emerging and are OIs capable of causing diarrhoeal disease associated with HIV...

2017
Ahmad KHOSRAVI Iraj SHARIFI Alireza FEKRI Alireza KERMANIZADEH Mehdi BAMOROVAT Mahshid MOSTAFAVI Mohammad Reza AFLATOONIAN Alireza KEYHANI

Background Cutaneous leishmaniasis (CL) is associated with a broad and complex clinical spectrum of diseases. The objectives of this study were to assess the clinical features and identification of the causative agents of CL in a well-known focus of anthroponotic CL (ACL) caused by Leishmania tropica, southeast Iran. Methods This study was performed randomly as a descriptive cross-sectional s...

2014
Annette Ives Slavica Masina Patrik Castiglioni Florence Prével Mélanie Revaz-Breton Mary-Anne Hartley Pascal Launois Nicolas Fasel Catherine Ronet

Infections with Leishmania parasites of the Leishmania Viannia subgenus give rise to both localized cutaneous (CL), and metastatic leishmaniasis. Metastasizing disease forms including disseminated (DCL) and mutocutaneous (MCL) leishmaniasis result from parasitic dissemination and lesion formation at sites distal to infection and have increased inflammatory responses. The presence of Leishmania ...

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