Tablet that disintegrate rapidly in the mouth are convenient for patient who have difficulty in swallowing conventional dosages forms. Although various formulation technologies like Zydis Technology, Durasolve Technology, Orasolve Technology, Flash Dose Technology, Wow Tab Technology, Flash Tab Technology, Quicksolv Technology, Lyos Technology, Fast Melt Technology and Zip-lets Technology are u...

J. Arya , Y-W. Chen , K. Dewitt , Y-W. Chiang , M. R. Prausnitz 1 1 Georgia Institute of Technology, 2 Merial Ltd. Purpose To stabilize rabies DNA vaccine in a dissolving microneedle patch and evaluate immunogenicity and dose sparing in dogs. Rabies is mainly a disease of animals, whereas humans get rabies primarily when they are bitten by dogs. Vaccinating domestic dogs and other animals has r...

A reactive fluid dissolving a uniform porous material triggers an instability in the dissolution front, leading to spontaneous formation of pronounced well-spaced channels in the surrounding rock matrix. The concentration field within the dissolving region contains two different length scales, upstream (no reaction) and downstream of the front position. Previous investigations of the reactive-i...

P systems are parallel molecular computing models based on processing multisets of objects in cell-like membrane structures. Recently, Petr Sosı́k has shown that a semi-uniform family of P systems with active membranes and 2-division is able to solve the PSPACE-complete problem QBF-SAT in linear time; he has also conjectured that the membrane dissolving rules of the (d) type may be omitted, but ...

Starting from a compositional operational semantics of transition P Systems we have previously defined, we face the problem of developing an axiomatization that is sound and complete with respect to some behavioural equivalence. To achieve this goal, we propose to transform the systems into a unique normal form which preserves the semantics. As a first step, we introduce axioms which allow the ...