The aim of the present study was to investigate the correlation between circulating tumor cells (CTC) and D-dimer (D-D) and platelet (PLT) in patients with pulmonary malignancies. A total of 98 patients with lung cancer admitted to West China Hospital, Sichuan University, from June 2016 to February 2017 were enrolled in the present study. D-D and PLT levels were measured in the fasting elbow ve...

Background: Cancer Antigen 15-3, a derivative of a large transmembrane glycoprotein polymorphic epithelial mucin derived from MUC1 gene is a reliable marker in identifying patients who would benefit most from adjuvant therapy. Materials & Methods: Aimed at assessing the overall risk, possibility of distant metastasis and need for adjuvant therapy we assessed the role of pre-operative CA 15-3 an...

PURPOSE To investigate the diagnostic performance of circulating tumor cells (CTC) in discrimination between primary lung cancer and nonmalignant diseases as well as in prediction of distant metastasis. PATIENTS AND METHODS We prospectively evaluated CTCs in 7.5-mL samples of peripheral blood sampled from patients with a suspicion or a diagnosis of primary lung cancer. A semiautomated system ...

PURPOSE To evaluate the diagnostic power of hybrid intravoxel incoherent motion (IVIM)-diffusion kurtosis imaging (DKI) model parameters in pretreatment for the prediction of future distant metastasis in head and neck squamous cell carcinoma (HNSCC) patients. MATERIALS AND METHODS We retrospectively evaluated 49 HNSCC patients who underwent curative chemoradiation therapy. Diffusion-weighted ...

BACKGROUND AND AIMS This study aimed to access possible relationships between breast cancer subtypes and sites of distant metastasis in breast cancer. RESULTS A total of 243,896 patients, including 226,451 cases in control groups were identified. Bone metastasis was found in 8848 cases, compared with 1,000 brain metastasis cases, 3434 liver metastasis cases and 4167 lung metastasis cases. Pat...

In order to know the associations between multifocality (MF), without related multicentricity (MC), and common clinical and biological parameters, and posterior influence in breast carcinoma behavior, we have developed this study. 816 successive women affected from invasive breast carcinomas, of which 96 were multifocal and 720 nonmultifocal were included in the study. We considered age, size, ...

Mutation analysis of circulating tumor DNA (ctDNA) has recently been introduced as a noninvasive tumor monitoring method. In this study, we tested the mass spectrometric-based MassARRAY platform for multiplexed gene mutation analysis of plasma samples from colorectal cancer (CRC) patients. A total of 160 patients, who underwent curative resection of either primary or metastatic CRC harboring KR...

Thyroid carcinomas constitute more than 90% of all endocrine cancers. In differentiated thyroid carcinomas for which the rate of a 10-year survival is 80-95%; distant metastasis is rarely seen [1]. distant metastases at the time of diagnosis vary between 1% and 9% in different series in the literature. In their series, Ozkan et al., have reported a bone metastasis at the rate of 3.9% in differe...

Uterine leiomyosarcoma (ULC) is an uncommon neoplasm characterized by poor prognosis, it can predispose to distant metastasis, causing various symptomatic presentations. We present a unique case of large heterogeneous mass in the lung cavity arising from ULC, with complete absence pulmonary symptoms and concurrent coronavirus disease 2019 (COVID-19) infection. A high degree clinical suspicion r...

BACKGROUND Despite better prognosis, there is a group of oropharyngeal squamous cell carcinoma (SCC) human papillomavirus (HPV)+ patients who experience treatment failure and succumb to distant metastasis. METHODS Seventy-eight previously untreated patients nested in a concurrent chemoradiation protocol were reviewed to correlate patterns of local-regional tumor extent to distant metastasis. ...