BACKGROUND/AIMS To evaluate the clinical efficacy and safety of combined repeated Ozurdex and macular laser therapy (MLT) compared with MLT monotherapy in participants with visual impairment due to centre-involving diabetic macular oedema (DMO). METHODS 80 patients with best corrected visual acuity (BCVA) between 54 and 78 ETDRS letters due to centre-involving DMO were randomised to combinati...

PURPOSE (1) The purpose of this study was to describe significance and prevalence of the newly reported pearl necklace spectral domain optical coherence tomography (SDOCT) sign, in diabetic macular edema (DMO), (2) to track the course of this sign over a period of at least 10 months. MATERIALS AND METHODS The pearl necklace SDOCT sign refers to hyperreflective dots in a contiguous ring around...

BACKGROUND This therapeutic drug monitoring (TDM) study aimed to determine the role of olanzapine (OLZ) and N-desmethyl-OLZ (DMO) levels in the therapeutic efficacy of OLZ in patients with schizophrenia. METHOD Plasma concentrations of OLZ (COLZ) and DMO (CDMO) in schizophrenic patients 12 hours post-dose were assessed. The correlations of COLZ and CDMO with the various scores of the Positive...

Tragedi Kanjuruhan pada 1 Oktober tahun 2022 merupakan tragedi sepak bola dengan korban jiwa terbanyak kedua sepanjang sejarah dunia. Union of European Football Associations (UEFA) juga turut berbela sungkawa melakukan hening cipta (moment silence) pertandingan liga mereka. ini memunculkan gerakan sosial dan aktivisme digital (DMO) melalui tagar #UsutTuntas. Data set yang di crawling menggunaka...

PURPOSE The influence of the modified process in the fiber-reinforced post and resin core foundation treatment on the fracture resistance and failure pattern of premolar was tested in this study. MATERIALS AND METHODS Thirty-six human mandibular premolars were divided into 4 groups (n = 9). In group DCT, the quartz fibre post (D.T. Light-post) was cemented with resin cement (DUO-LINK) and a c...

The mechanisms of action of antiepileptic drugs effective against generalized absence seizures (antiabsence AEDs) remain uncertain. Antiabsence AEDs are generally effective against seizures induced in experimental animals by pentylenetetrazol (PTZ) and methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM), drugs which reduce GABAergic inhibition. Thus, antiabsence AEDs have been sugg...

Al~tmct. The extracellular acid-base status of the freshwater rainbow trout (Salmo gairdneri) was continuously monitored during 24 h normoxia (Pxo: = 120-150 tort; control), 72 h hyperoxia (Pioz = 500-600 tort) and 24 h return to normoxia. Hyperoxla induced a marked respiratory acidosis (ApHe = -0.23 unit) due to a 3-fold elevation in arterial CO 2 tension which was completely compensated over ...

The objective of the present work is to develop finite element based optimization techniques for laminated composite shell structures. The platform of implementation is the finite element based analysis and design tool MUST (MUltidisciplinary Synthesis Tool) and a number of features have been added and updated. This includes an updated implementation of finite elements for shell analysis, tools...

Dimethoxybenzidine (DMO) and dimethylbenzidine (DM) are used to synthesize dyes such as C.I. Direct Blue 15 and C.I. Acid Red 114, respectively. These commercially used dyes are metabolically degraded to DMO or DM in the intestinal tract of rodents and subsequently DMO and DM are absorbed into the blood stream. Animals were exposed to DMO, DM, or the dyes in the drinking water. Tumors obtained ...

Los análisis tafonómicos específicos sobre la frecuencia de partes anatómicas en conjuntos óseos pinnípedos han sido menos frecuentes comparación con los mamíferos terrestres. Sin embargo, estudios zooarqueológicos permiten señalar interdependencia entre valores densidad mineral ósea (DMO) y índices utilidad económica (%MUI), lo cual conlleva incertidumbre ponderar las estrategias transporte po...