We use the abstract tile assembly model of Winfree [6], which models the aggregation of monomers called tiles that attach one at a time to a growing structure, starting from a single seed tile, in which bonds (“glues”) on the tile are specific (glues only stick to glues of the same type on other tiles) and cooperative (so that multiple weak glues are necessary to attach a tile). The general ide...

Nucleic acid nanotechnology has enabled researchers to construct a wide range of multidimensional structures in vitro. Until recently, most DNA-based structures were assembled by thermal annealing using high magnesium concentrations and nonphysiological environments. Here, we describe a DNA self-assembly system that can be tuned to form a complex target structure isothermally at any prescribed ...

The tile assembly model is a highly distributed parallel model of molecular computation. Plenty of experiments have proved that the simple binary arithmetic could be fulfilled by the process of self-assembly of DNA (deoxyribonucleic acid) tiles. Finite field GF(2 n ) is one of the most commonly used mathematic sets. A DNA computing system was designed based on the tile assembly model and applie...

Self-assembling DNA nanostructures based on rationally designed DNA branch junction molecules has recently led to the construction of patterned supramolecular structures with increased complexities. An intrinsic value of DNA tiles and patterns lies in their utility as molecular pegboard for deterministic positioning of molecules or particles with accurate distance and architectural control. Thi...

Self-assembly has been recognised as a ubiquitous aspect of modern chemistry. Our understanding and applications of self-assembly are substantially based on what has been learned from biochemical systems. In this review, we describe various aspects of self-assembly commencing with an account of the soft structures that are available by assembly of surfactant amphiphiles, which are important sci...

The self-assembly of DNA-modified silica nanoparticles in microfluidic droplets was investigated using a new fluorosurfactant. Such can be used for cell encapsulation.

The vision of nanoscale self-assembly research is the programmable synthesis of macroscale structures with controlled long and short-range order that exhibit a desired set of properties and functionality. However, strategies to reliably isolate and manipulate the nanoscale building blocks based on their size, shape, or chemistry are still in their infancy. Among the promising candidates, DNA-me...

DNA computing 1 potentially provides a degree of parallelism far beyond that of conventional silicon-based computers. A number of researchers 2 have experimentally demonstrated DNA computing in solving instances of the satisfiability problems. Self-assembly of DNA nanostructures is theoretically an efficient method of executing parallel computation where information is encoded in DNA tiles and ...