نتایج جستجو برای: dose accumulation
تعداد نتایج: 452555 فیلتر نتایج به سال:
AIM To determine the role of G0/G1 switch gene 2 (G0S2) and its transcriptional regulation in palmitate-induced hepatic lipid accumulation. METHODS HepG2 cells were treated with palmitate, or palmitate in combination with CCAAT/enhancer binding protein (C/EBP)β siRNA or G0S2 siRNA. The mRNA expression of C/EBPβ, peroxisome proliferator-activated receptor (PPAR)γ and PPARγ target genes (G0S2, ...
Persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in Nigeria. Hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of P. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in Wistar rats to substantiate this claim. The chloroform and met...
To clarify toxic effects of long-term oral administration of low dose cadmium (Cd) on the liver and kidney, six groups of female Sprague-Dawley rats were fed a diet containing Cd-polluted rice or CdCl2 at concentrations up to 40 ppm, and killed after 12, 18, and 22 months. With toxicological parameters, including histopathology, there was no evidence of Cd-related hepato-renal toxicity, despite...
introduction: esophageal cancer is one of the most frequently occurring cancers in iran and having a high incidence rate among other countries. radiotherapy is one of the three methods (surgery, radiotherapy and chemotherapy) for radical or palliative treatment of esophageal cancer. in this method of treatment, the organs such as heart and spinal cord are regarded as organs at r...
introduction radiation exposures from diagnostic medical examinations are generally low and are almost always justified by the benefits of accurate diagnosis of possible disease conditions. therefore, entrance skin dose (esd), body organ dose (bod), and effective dose (ed) from adult patients undergoing routine thorax posterior-anterior (pa) and thorax right lateral (rlat) were estimated in uni...
Orally administered Ag2S quantum dots (QDs) rapidly cross the small intestine and are taken up by liver. Metformin nicotinamide mononucleotide (NMN) target metabolic aging processes within This study examined pharmacology toxicology of QD-based nanomedicines as carriers metformin NMN in young old mice, determining if their therapeutic potency reduced effects associated with could be improved. P...
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