We present an algorithm suitable for the calculation of the RBE-weighted dose for moving targets with a scanned particle beam. For verification of the algorithm, we conducted a series of cell survival measurements that were compared to the calculations. Calculation of the relative biological effectiveness (RBE) with respect to tumor motion was included in the treatment planning procedure, in or...

The high density and atomic number of hip prostheses for patients undergoing pelvic radiotherapy challenge our ability to accurately calculate dose. A new clinical dose calculation algorithm, Monte Carlo, will allow accurate calculation of the radiation transport both within and beyond hip prostheses. The aim of this research was to investigate, for both phantom and patient geometries, the capa...

abstract background: accurate methods of radiation therapy dose calculation. there are different monte carlo codesfor simulation of photons, electrons and the coupled transport of electrons and photons. mcnpis a general purpose monte carlo code that can be used for electron, photon and coupledphoton-electron transport.monte carlo simulation of radiation transport is considered to be one of the ...

The aim of this study is to compare the recent Eclipse Acuros XB (AXB) dose calculation engine with the Pinnacle collapsed cone convolution/superposition (CCC) dose calculation algorithm and the Eclipse anisotropic analytic algorithm (AAA) for stereotactic ablative radiotherapy (SAbR) treatment planning of thoracic spinal (T-spine) metastases using IMRT and VMAT delivery techniques. The three c...

Kanji Hioka Graduate School of Science and Engineering, Yamaguchi University 1677-1 Yoshida, Yamaguchi 753-8512, Japan [email protected] Yoshimasa Miwa Graduate School of Science and Engineering, Yamaguchi University 1677-1 Yoshida, Yamaguchi 753-8512, Japan [email protected] Chen Li Human Genome Center, University of Tokyo 4-6-1 Shirokanedai, Minatoku, Tokyo 108-8639, Ja...

The use of small fi elds in radiotherapy techniques has increased substantially, in particular in stereotactic treatments and large uniform or nonuniform fi elds that are composed of small fi elds, such as for intensity-modulated radiation therapy (IMRT). This clinical perspective will focus on an experimental evaluation of the dose calculation accuracy of the anisotropic analytical algorithm (...

Background: In radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. In this study, the two available calculation algorithms of the Varian Eclipse 8.6 treatment planning system(TPS), the anisotropic analytic algorithm (AAA) and pencil-beam convolution (PBC) was used to compare measured and calculated peripheral dose distributi...

High dose rate brachytherapy has attained the good local control for cervix cancer because radioactive source can be put close to tumors, resulting in increasing the dose delivery per one fraction. However, quality assurance must be accompanied to reduce severe complication. We verified the dose distribution around the source by comparing measured dose with calculated dose by Radiation Therapy ...

The Leksell GammaPlan software version 10 introduces a CT image-based segmentation tool for automatic skull definition and a convolution dose calculation algorithm for tissue inhomogeneity correction. The purpose of this work was to evaluate the impact of these new approaches on routine clinical Gamma Knife treatment planning. Sixty-five patients who underwent CT image-guided Gamma Knife radios...