BACKGROUND Systemic sclerosis (scleroderma; SSc) is an orphan disease with the highest case-specific mortality of any connective-tissue disease. Excessive collagen deposit in affected tissues is a key for the disease's pathogenesis and comprises most of the clinical manifestations. Lidocaine seems to be an alternative treatment for scleroderma considering that: a) the patient's having excessive...

backgroundabout 15 to 40% of children with seizures are refractory to standard anti-epileptic drugs and for such patients, other treatments such as surgery and the ketogenic diet can reduce seizure frequency. melatonin is a natural pineal gland hormone. the use of melatonin for controlling pediatric seizures is still controversial. this study aimed to evaluate the effect of melatonin on seizure...

background and aims. standard treatment of oral lichen planus (olp) includes topical or systemic corticosteroids that have many adverse effects. a trend toward alternative natural or herbal drugs has attended recently. this study was conducted to evaluate the effect of quercetin in treatment of erosive-atrophic olp. materials and methods. thirty patients participated in this randomized clinical...

the aim of this study was to evaluate the effects of atorvastatin on negative symptoms in patients with chronic schizophrenia. the study was a prospective, double-blind, 6-week trial. forty patients participated in the study; 19 patients were assigned to the atorvastatin group as well as 21 patients to the placebo group. for assessing negative signs, we used scale for the assessment of negative...

how to cite this article: fayyazi a, khajeh a, ghazavi a, sangestani m. omega 3 in childhood migraines; a double blind randomized clinical trial. iran j child neurol. winter 2016; 10(1):9-13. abstract objective the effect of using omega-3 to prevent migraine attacks has been raised in recent studies. the majority of these studies have been conducted in adults. conversely, other studies have yet...