Diamond-coated tools often fail due to coating graphitization and delamination caused by poor adhesion, large contact stress, thermochemical reactions. To address these issues, this research utilized a combination of micro-nano double-layer diamond coating, WS2 micro-textures. The inhibits the through transfer film mechanism, while micro-textures nanocrystalline store WS2, resulting in prolonge...

Liquid-filled pectinate capsules have a large potential for the controlled and site-specific delivery of liquid drugs. Earlier studies have shown that pure pectinate capsules can store drugs only for a few minutes. Here, we show that the retention time can be extended to several hours by coating the capsules with the natural resin shellac. A bilberry extract containing anthocyanins with promisi...

In this paper we investigate the role of micropatterning and molecular coating for cell culture and differentiation of neuronal cells (Neuro2a cell line) on a polydimethylsiloxane substrate. We investigate arrays of micrometric grooves (line and space) capable to guide neurite along their axis. We demonstrate that pattern dimensions play a major role due to the deformation of the cell occasione...

We demonstrate the application of a novel smart surface to modulate the orientation of immobilized double stranded DNA (dsDNA) and the conformation of a polymer scaffold through variation in buffer pH and ionic strength. An amphoteric poly(dimethylacrylamide) based coating containing weak acrylamido acids and bases, which are copolymerized together with the neutral monomer, is covalently bound ...

A method for reducing the reflections from silicon optics at terahertz frequencies has been investigated. In this study, we used thin films of parylene as an anti-reflection (AR) layer for silicon optics and show low-loss behavior well above 1 THz. Transmittance spectra are acquired on double-sided-parylene-coated, high-resistivity, single-crystal silicon etalons between 0.45 THz and 2.8 THz. M...

The atomic layer deposition (ALD) technology is introduced to enhance the sensitivity of optical fiber cladding mode to surrounding refractive index (SRI) variation. The highly uniform Al2O nanofilm was deposited around the double cladding fiber (DCF) which presents cladding mode resonant feature. With the high refractive index coating, the cladding mode resonant spectrum was tuned. And the sen...

In the present study, we aimed to prepare rhubarb total anthraquinones oral colon-specific drug delivery granules (RTA-OCDDGN) for delivering rhubarb free anthraquinones to colon. RTA-OCDD-GN was successfully prepared through a double-layer coating process using chitosan as an inner layer and Eudragit S100 as an outer enteric coating layer. The pharmacodynamics and toxicological results showed ...

In situ quantification of localizedweathering processes on basalt flows inNewMexico andHawaii demonstrates that small-area factors can be more important than other more readily observable factors. Further, it demonstrates that the factorial concept of the Pope Boundary-Layer weathering model is partially solvable, that organicweathering can accentuate glassweathering (with implications for clim...

Microfluidic devices can perform multiple laboratory functions on a single, compact, and fully integrated chip. However, fabrication of microfluidic devices is difficult, and current methods, such as glass-etching or soft-lithography in PDMS, are either expensive or yield devices with poor chemical robustness. We introduce a simple method that combines the simple fabrication of PDMS with superi...

We aimed to embed silica optical fibers in composites (epoxy vinyl ester matrix reinforced with E-glass unidirectional fibers in mass fraction of 60%) in order to further monitor the robustness of civil engineering structures (such as bridges). A simple system was implemented using two different silica optical fibers (F1-double coating of 172 µm diameter and F2-single coating of 101.8 µm diamet...