نتایج جستجو برای: down function

تعداد نتایج: 1391293  

Journal: :Advances in Digestive Medicine 2023

Hepatitis C virus (HCV) is both hepatotropic and lymphotropic in human bodies. Its cytopathic nature leads to a wide category of extrahepatic manifestations. The kidney one the target organs/systems that HCV involves. A poor renal function chronic hepatitis (CHC) patients may be due immune complex depositions causes glomerular or tubulointerstitial injuries. Increasing comorbidities than genera...

Journal: :American Journal on Intellectual and Developmental Disabilities 2020

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1997
P G Nelson S Fitzgerald S I Rapoport E A Neale Z Galdzicki V Dunlap L Bowers D v Agoston

Trisomy 21 (Down syndrome) is associated with a high incidence of Alzheimer disease and with deficits in cholinergic function in humans. We used the trisomy 16 (Ts16) mouse model for Down syndrome to identify the cellular basis for the cholinergic dysfunction. Cholinergic neurons and cerebral cortical astroglia, obtained separately from Ts16 mouse fetuses and their euploid littermates, were cul...

Journal: :Alzheimers & Dementia 2023

Background Higher engagement in moderate-to-vigorous physical activity (PA) is related to better cognitive functioning neurotypical adults; however, little known about the impact of PA on aging adults with Down syndrome (DS). Individuals DS have three copies chromosome 21, which includes gene for amyloid precursor protein, resulting an increased risk for/earlier onset Alzheimer’s disease. The g...

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