objective: druggability of a target protein depends on the interacting micro-environment between the target protein and drugs. therefore, a precise knowledge of the interacting micro-environment between the target protein and drugs is requisite for drug discovery process. to understand such micro-environment, we performed in silico interaction analysis between a human target protein, dipeptidyl...

the narcotic drugs business find its abusement, nowadays, have been one of the most basic political, economic, health, cultural anti-family disorders in almost all over the world. despite all technologic anti cultural developments, it seems that the tendency and interest of producers, distributors and users of these drugs in all different age levels are growing up increasingly. unfortunately, t...

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

lymphomas are solid tumors of immune system and non-hodgkin lymphomas (nhl) is the most prevalent lymphomas; with wide ranges of histological and clinical features, it is so difficult to identify them. herein, various bioinformatics tools (such as gene differential expressions, epigenetics and protein analysis) employed to find new treatment approach for nhl based on gene expression variation b...

background: substance abuse is as a health-related behavioral problem, which more or less all countries have to deal with it. this behavior has broad effects on the individual and societal level, thereforeidentifying factors associated with this behavior is necessary. this study compared rates of depression, anxiety and stress between drug abusers and non-abusers. methods: this was a descriptiv...